Evidence map›Paper›PMID 40491994›Full record

ArticleFrontiers in public health2025

Graciela Russomando, Norma Fariña, Selilah Amour, Lorena Grau, Rosa Guillen, Sonia Abente, Monserrat Aldama, Ingrid Hahn, Hector Castro, Mélina Messaoudi and 4 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Graciela RussomandoInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, San Lorenzo, Paraguay.
Norma FariñaLaboratorio San Roque, Asunción, Paraguay.
Selilah AmourService d'Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France.
Lorena GrauHospital Pediátrico "Niños de Acosta Ñu", Ministerio de Salud Pública, San Lorenzo, Paraguay.
Rosa GuillenInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, San Lorenzo, Paraguay.
Sonia AbenteInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, San Lorenzo, Paraguay.
Monserrat AldamaInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, San Lorenzo, Paraguay.
Ingrid HahnHospital Pediátrico "Niños de Acosta Ñu", Ministerio de Salud Pública, San Lorenzo, Paraguay.
Hector CastroHospital Pediátrico "Niños de Acosta Ñu", Ministerio de Salud Pública, San Lorenzo, Paraguay.
Mélina MessaoudiFondation Mérieux, Lyon, France.
Zunilda SanchezInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, San Lorenzo, Paraguay.
Valentina PicotFondation Mérieux, Lyon, France.
Florence Komurian-PradelFondation Mérieux, Lyon, France.
Milen MilenkovFondation Mérieux, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Infections due to Methods: Nasopharyngeal samples (NP) were obtained from 420 child/adult pairs between September 2018 and October 2019. Detection, serotyping, pneumococcal isolation and antibiotic susceptibility testing were performed using standardized protocols. Additionally, vaccine impact on serotype prevalence was assessed by comparison with a group of 100 healthy carriers under 5 years of age, recruited at the same hospital between 2010 and 2014, prior to vaccine introduction. Results: We observed higher pneumococcal carriage in children (39%) than in adults (20%) and limited intrafamilial transmission. Vaccine serotypes continue to circulate among children despite vaccination, accompanied by a rise in non-vaccine serotypes. Almost 11% of fully vaccinated children still carried vaccine serotypes. Antibiotic resistance to beta-lactams and macrolides has increased; nearly one-third of the isolates were multidrug resistant while multi-drug resistant pediatric isolates were predominantly associated with serotypes 19F and 19A. Conclusion: Our findings reveal worrying trends in the epidemiology of

Indexed as

Carrier StateDrug Resistance, BacterialPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAdolescentAdultAnti-Bacterial AgentsChildChild, PreschoolFemaleHumansInfantMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsPneumococcal VaccinesadultscarriagechildrenParaguayserotypesStreptococcus pneumoniaevaccine

Identifiers

PMID40491994
PMCPMC12146381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.