Evidence map›Paper›PMID 40491967›Full record

ReviewMedComm2025

Deep Learning in Digital Breast Tomosynthesis: Current Status, Challenges, and Future Trends.

Ruoyun Wang, Fanxuan Chen, Haoman Chen, Chenxing Lin, Jincen Shuai, Yutong Wu, Lixiang Ma, Xiaoqu Hu, Min Wu, Jin Wang and 3 more

Abstract readReview
In one paragraph

Review in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ruoyun WangOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Fanxuan ChenOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Haoman ChenOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Chenxing LinOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Jincen ShuaiUCSC Baskin School of Engineering University of California Santa Cruz California USA.
Yutong WuWenzhou Medical University Wenzhou China.
Lixiang MaDepartment of Anatomy Histology & Embryology School of Basic Medical Sciences Fudan University Shanghai China.
Xiaoqu HuWenzhou Medical University Wenzhou China.
Min WuOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Jin WangOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Qi ZhaoOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.ORCID https://orcid.org/0000-0001-9713-1864
Jianwei ShuaiOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou China.
Jingye PanKey Laboratory of Intelligent Treatment and Life Support for Critical Diseases of Zhejiang Province Wenzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high-resolution three-dimensional (3D) images generated with digital breast tomosynthesis (DBT) in the screening of breast cancer offer new possibilities for early disease diagnosis. Early detection is especially important as the incidence of breast cancer increases. However, DBT also presents challenges in terms of poorer results for dense breasts, increased false positive rates, slightly higher radiation doses, and increased reading times. Deep learning (DL) has been shown to effectively increase the processing efficiency and diagnostic accuracy of DBT images. This article reviews the application and outlook of DL in DBT-based breast cancer screening. First, the fundamentals and challenges of DBT technology are introduced. The applications of DL in DBT are then grouped into three categories: diagnostic classification of breast diseases, lesion segmentation and detection, and medical image generation. Additionally, the current public databases for mammography are summarized in detail. Finally, this paper analyzes the main challenges in the application of DL techniques in DBT, such as the lack of public datasets and model training issues, and proposes possible directions for future research, including large language models, multisource domain transfer, and data augmentation, to encourage innovative applications of DL in medical imaging.

Indexed as

deep learningdigital breast tomosynthesisearly breast cancer screeningmedical image analysispublic database

Identifiers

PMID40491967
PMCPMC12146671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.