Evidence map›Paper›PMID 40491893›Full record

ArticleCase reports in dermatology

Therapy-Resistant Erosions in the Genital Area of Elderly Patients: A Differential Diagnostic Challenge - A Case Report.

Martin Gschnell, Iris Hennighausen, Can Alpagut, Julia Nadina Föhr, Jacqueline Kussini, Lisa Krönig

Abstract read
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Article in Case reports in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Martin GschnellDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.
Iris HennighausenDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.
Can AlpagutDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.
Julia Nadina FöhrDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.
Jacqueline KussiniDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.
Lisa KrönigDepartment of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Genital erosions occur in many dermatological conditions and can sometimes be difficult to classify, especially in older patients with multiple morbidities. Case Presentation: We report the case of an 81-year-old patient with therapy-resistant genital erythema. Under topical antifungal therapy for a suspected diagnosis of Candida intrigue, the scrotal findings continued to progress, accompanied by genital erosions and new erosions on the nose and right knee. With evidence of IgG and C3 deposition on the basement membrane on direct immunofluorescence and subepidermal cleft formation on histology, a diagnosis of bullous pemphigoid with predominant genital involvement was made. Conclusion: In conclusion, this case study illustrates that skin biopsies should be taken in cases of therapy-resistant erythema with erosions in order to clarify the dignity and ultimately to be able to adapt the treatment. In addition, it is important to examine the entire integument, including the mucous membranes close to the skin, to avoid overlooking groundbreaking findings. Bullous pemphigoid is the most common blistering autoimmune skin disease and occurs mainly in older people. However, the classic picture of bulging blisters is not always present. Bullous pemphigoid may masquerade clinically as pruritic eczema, erythroderma, or erosions. Predominant genital involvement has only been described in a few case reports.

Indexed as

Bullous pemphigoidGenital bullous pemphigoidGenital erosions

Identifiers

PMID40491893
PMCPMC12148320

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