Evidence map›Paper›PMID 40491885›Full record

ArticleWorld journal of critical care medicine2025

Incidence and outcome of rhabdomyolysis after type A aortic dissection surgery: A retrospective analysis.

Praveen C Sivadasan, Cornelia S Carr, Abdul Rasheed A Pattath, Samy Hanoura, Suraj Sudarsanan, Hany O Ragab, Hatem Sarhan, Arunabha Karmakar, Rajvir Singh, Amr S Omar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rhabdomyolysis after strenuous exercise: A case report.SAGE open medical case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Praveen C SivadasanCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar. psivadasan@hamad.qa.
Cornelia S CarrDepartment of Clinical Surgery, College of Medicine, Qatar University, Doha 3050, Qatar.
Abdul Rasheed A PattathCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.
Samy HanouraCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.
Suraj SudarsananCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.
Hany O RagabCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.
Hatem SarhanDepartment of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.
Arunabha KarmakarDepartment of Medical Education, Hamad Medical Corporation, Doha 3050, Qatar.
Rajvir SinghDepartment of Medical Research, Hamad Medical Corporation, Doha 3050, Qatar.
Amr S OmarCardiac Anesthesia and ICU Section, Department of Cardiothoracic Surgery, Hamad Medical Corporation, Doha 3050, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRhabdomyolysis (RML) as an etiological factor causing acute kidney injury (AKI) is sparsely reported in the literature.

aimTo study the incidence of RML after surgical repair of an ascending aortic dissection (AAD) and to correlate with the outcome, especially regarding renal function. To pinpoint the perioperative risk factors associated with the development of RML and adverse renal outcomes after aortic dissection repair.

methodsRetrospective single-center cohort study conducted in a tertiary cardiac center. We included all patients who underwent AAD repair from 2011-2017. Post-operative RML workup is part of the institutional protocol; studied patients were divided into two groups: Group 1 with RML (creatine kinase above cut-off levels 2500 U/L) and Group 2 without RML. The potential determinants of RML and impact on patient outcome, especially postoperative renal function, were studied. Other outcome parameters studied were markers of cardiac injury, length of ventilation, length of stay in the intensive care unit), and length of hospitalization.

resultsOut of 33 patients studied, 21 patients (64%) developed RML (Group RML), and 12 did not (Group non-RML). Demographic and intraoperative factors, notably body mass index, duration of surgery, and cardiopulmonary bypass, had no significant impact on the incidence of RML. Preoperative visceral/peripheral malperfusion, though not statistically significant, was higher in the RML group. A significantly higher incidence of renal complications, including de novo postoperative dialysis, was noticed in the RML group. Other morbidity parameters were also higher in the RML group. There was a significantly higher incidence of AKI in the RML group (90%) than in the non-RML group (25%). All four patients who required de novo dialysis belonged to the RML group. The peak troponin levels were significantly higher in the RML group.

conclusionIn this study, we noticed a high incidence of RML after aortic dissection surgery, coupled with an adverse renal outcome and the need for post-operative dialysis. Prompt recognition and management of RML might improve the renal outcome. Further large-scale prospective trials are warranted to investigate the predisposing factors and influence of RML on major morbidity and mortality outcomes.

Indexed as

Acute kidney injuryAscending aortic dissection surgeryOpen heart surgeryPostoperative renal outcomeRhabdomyolysisType A aortic dissection

Identifiers

PMID40491885
PMCPMC11891855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.