Evidence map›Paper›PMID 40491842›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Dermoscopy and Pathological Correlation in Different Grades of Actinic Keratosis and Squamous Cell Carcinoma.

Xiao Li, Jiachen Sun, Hua Zhang, Chunlei Zhang, Weiwei Li

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao LiDepartment of Dermatology, Peking University Third Hospital, Beijing, People's Republic of China.ORCID 0000-0002-1841-6552
Jiachen SunDepartment of Dermatology, Peking University Third Hospital, Beijing, People's Republic of China.ORCID 0000-0002-9578-229X
Hua ZhangResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, People's Republic of China.ORCID 0000-0002-9103-4796
Chunlei ZhangDepartment of Dermatology, Peking University Third Hospital, Beijing, People's Republic of China.ORCID 0000-0003-1685-2198
Weiwei LiDepartment of Dermatology, Peking University Third Hospital, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Squamous Cell Carcinoma (SCC) is a common skin malignancy arising from keratinocytes and can develop from Actinic Keratosis (AK). Establishing reliable criteria for early differentiation of AK grades and SCC is essential for timely intervention and regular examination. Purpose: This study investigates clinical and dermoscopic criteria for AK and SCC grades, exploring the pathological basis of features to aid clinicians in assessing disease status and guiding treatment. Patients and Methods: Clinical and dermoscopic images of AK and SCC patients were assessed by three independent researchers. Key dermoscopic features were identified and correlated with pathological findings. Results: A total of 106 AK cases (36 AK I, 24 AK II, 46 AK III; 33 PRO I, 40 PRO II, 33 PRO III) and 33 SCC cases were included. Clinical positive predictors for SCC included solitary lesions ( Conclusion: Dermoscopy offers a non-invasive and effective method for assessing lesion malignancy across various grades of AK and SCC, reflecting their pathological features and aiding clinical diagnosis while potentially reducing unnecessary biopsies.

Indexed as

actinic keratosisdermatological imagingsquamous cell carcinomatumor microenvironment

Identifiers

PMID40491842
PMCPMC12146408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.