ReviewResuscitation plus2025
Impact of prehospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest on survival with good neurological function: a systematic review and meta-analysis.
Review in Resuscitation plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Operational assumptions underlying extracorporeal resuscitation eligibility models.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Article
- Early active normothermia versus no temperature control in a porcine model of extracorporeal cardiopulmonary resuscitation.Intensive care medicine experimental · 2026Article
- Ethics in prehospital extracorporeal cardiopulmonary resuscitation.Resuscitation plus · 2026Article
- Characteristics and outcomes of younger adults with out-of-hospital cardiac arrest resuscitated with extracorporeal membrane oxygenation: a nationwide study.BMC cardiovascular disorders · 2026Observational
- The impact of interdisciplinary cardiac arrest teams on paramedic practise: an interpretive qualitative study using reflexive thematic analysis.Resuscitation plus · 2026Article
- Cost effectiveness of pre-hospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest - An analysis of the PRECARE study.Resuscitation plus · 2026Article
- [Post-Resuscitation care in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Neurological outcomes and survival after prehospital ECPR: the impact of low-flow time.Frontiers in cardiovascular medicine · 2026Article
- Low-flow time and neurological outcomes in AMI patients undergoing ECPR: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Scoring the Importance of Patient Selection in Extracorporeal Cardiopulmonary Resuscitation and Non-Shockable Rhythm Cardiac Arrest: The START-ECPR Score.Journal of the American Heart Association · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: Prehospital extracorporeal cardiopulmonary resuscitation (ECPR) has been proposed to reduce delays in ECPR delivery in refractory out-of-hospital cardiac arrests (OHCA) and improve outcomes. Our aim was to synthesize the literature on outcomes of prehospital ECPR in OHCA, focusing on low-flow times (emergency call to extracorporeal blood flow) and survival with good neurological function, comparing them to in-hospital ECPR when possible. Methods: We conducted a systematic review and Results: Eight cohort studies involving 305 patients (84% male, mean age 57) were included. Survival with good neurological function was 25% (95%CI: 17-35%). Mean low-flow time was 59 min (95%CI: 46-72). Meta-regression showed a significant inverse association between low-flow time and good neurological outcomes (β = -0.0271, 95%CI: -0.0536 to -0.0006; p = 0.045). Compared to in-hospital ECPR, prehospital ECPR showed no significant difference in survival (RR 1.23, 95%CI: 0.35-4.38) but was associated with significantly shorter low-flow times (mean difference -30 min, 95%CI: -44 to -16). Conclusion: Prehospital ECPR is associated with a 25% rate of survival with good neurological function. Shorter low-flow times were associated with improved outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.