Evidence map›Paper›PMID 40491754›Full record

ArticleNMC case report journal2025

Hydrocephalus after Gamma Knife Surgery for Vestibular Schwannoma Resolved by Tumor Removal without Cerebrospinal Fluid Diversion: Report of Two Cases.

Miyuki Ogane, Iwao Yamakami, Shunsuke Kubota, Toru Serizawa, Yoshinori Higuchi

Abstract readCase Reports
In one paragraph

Article in NMC case report journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miyuki OganeDepartment of Neurosurgery, Chiba University Hospital, Chiba, Chiba, Japan.
Iwao YamakamiDepartment of Neurosurgery, Sosen Hospital, Chiba, Chiba, Japan.
Shunsuke KubotaDepartment of Neurosurgery, Chiba Medical Center, Chiba, Chiba, Japan.
Toru SerizawaTokyo Gamma Unit Center, Tsukiji Neurological Clinic, Tokyo, Japan.
Yoshinori HiguchiDepartment of Neurosurgery, Chiba University Hospital, Chiba, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrocephalus following Gamma Knife surgery for vestibular schwannoma is typically treated with cerebrospinal fluid diversion. However, additional cerebrospinal fluid diversion (shunt placement) causes a lifelong risk of shunt malfunction and infection. We report two cases of vestibular schwannoma in which the hydrocephalus with progressive tumor growth after Gamma Knife surgery was treated by an initial tumor removal, resolving hydrocephalus without cerebrospinal fluid diversion and causing long-term tumor control. Patient 1 underwent Gamma Knife surgery for a 22-mm tumor vestibular schwannoma of Koos grade III and developed symptomatic hydrocephalus with progressive tumor growth. Tumor removal at 17 months after Gamma Knife surgery resolved the hydrocephalus without tumor recurrence 8 years after surgery. Patient 2 underwent Gamma Knife surgery for an 18-mm tumor vestibular schwannoma of Koos grade IV and developed rapid tumor growth and symptomatic hydrocephalus 2 years after Gamma Knife surgery. Patient 2 underwent subtotal tumor removal at 40 months after Gamma Knife surgery resolving hydrocephalus without residual tumor progression at 14 years after Gamma Knife surgery. Subtotal tumor removal may be a primary treatment option in patients with vestibular schwannoma treated with Gamma Knife surgery and developing hydrocephalus with tumor progression. This might help avoid cerebrospinal fluid diversion with long-term tumor control.

Indexed as

gamma knife surgeryhydrocephalusvestibular schwannoma

Identifiers

PMID40491754
PMCPMC12148349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.