ArticleCureus2025
Acute Ischemic Stroke Secondary to Severe Anemia From Upper Gastrointestinal Bleeding: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia is increasingly recognized as a significant risk factor for ischemic stroke, contributing to cerebral hypoperfusion and exacerbating cerebrovascular events. This case report highlights the complex interplay between severe anemia and ischemic stroke in a 63-year-old male with a history of well-controlled hypertension and type 2 diabetes mellitus. The patient presented with acute neurological deficits, including slurred speech and left-sided weakness, which were later diagnosed as ischemic stroke. His condition was preceded by upper gastrointestinal bleeding from a pyloric channel ulcer, resulting in severe acute posthemorrhagic anemia and consequent hypovolemia. Anemia, often overlooked as a major stroke risk factor, was identified as a key contributor to the ischemic event. Potential mechanisms include reduced oxygen-carrying capacity, cerebral hypoperfusion due to volume loss, and endothelial dysfunction. Immediate management included blood transfusions to correct the anemia, intravenous proton pump inhibitors for gastrointestinal bleeding control, and clopidogrel for secondary stroke prevention. The patient's condition improved gradually, underscoring the importance of early recognition and treatment of anemia in stroke patients. This case emphasizes the need for comprehensive management of underlying anemia and cerebrovascular risk factors to optimize patient outcomes.
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