Evidence map›Paper›PMID 40491639›Full record

ArticleCureus2025

Intraocular Inflammation Following Faricimab Intravitreal Injection Treated With Sub-tenon Triamcinolone Acetonide Injection.

Shinnosuke Yasuda, Hiroki Tsujinaka, Takeyuki Nishiyama, Yutaro Mizusawa, Tetsuo Ueda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shinnosuke YasudaOphthalmology, Nara Medical University, Kashihara, JPN.
Hiroki TsujinakaOphthalmology, Nara Medical University, Kashihara, JPN.
Takeyuki NishiyamaOphthalmology, Nara Medical University, Kashihara, JPN.
Yutaro MizusawaOphthalmology, Nara Medical University, Kashihara, JPN.
Tetsuo UedaOphthalmology, Nara Medical University, Kashihara, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the management of intraocular inflammation (IOI) following faricimab intravitreal injection. Severe IOI was observed in three eyes (one eye with age-related macular degeneration (AMD) and two eyes in the same patient with diabetic macular edema (DME)). These three eyes had fine keratic precipitates, inflammatory cells in the anterior chamber, and vitreous opacity, with decreased best-corrected visual acuity (BCVA) in all patients. Blood tests did not reveal any abnormalities, and anterior chamber multiplex polymerase chain reaction and bacterial cultures were negative. Sub-tenon triamcinolone acetonide (STTA) injections improved anterior inflammation, vitreous opacity, and BCVA, although posterior iris synechia caused by inflammation persisted in one patient. Faricimab injection can induce IOI. In this study, IOI was managed with a STTA injection during the early stage of uveitis. Severe inflammation can lead to complications such as posterior iris synechia.

Indexed as

age-related macular degenerationdiabetic macular edemafaricimabintraocular inflammationintravitreal injectionsub-tenon triamcinolone acetonide injection

Identifiers

PMID40491639
PMCPMC12146440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.