ArticleCureus2025
Hemolytic Anemia Caused by Dynamic Left Ventricular Outflow Tract Obstruction Following Surgical Aortic Valve Replacement: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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3 authors.
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Abstract
Hemolysis following surgical aortic valve replacement (SAVR) is typically attributed to paravalvular leakage or prosthetic valve dysfunction. However, we present a rare case of hemolytic anemia caused by dynamic left ventricular outflow tract obstruction (LVOTO) due to septal hypertrophy following SAVR with a bioprosthetic valve. A 78-year-old woman underwent SAVR with annular enlargement via the Manougian procedure. Despite an uneventful intraoperative course and initial recovery, she developed progressive hemolysis postoperatively without evidence of valve dysfunction or paravalvular regurgitation. Echocardiography revealed dynamic LVOTO and moderate mitral regurgitation (MR). Conservative treatment, including beta blockers and calcium channel blockers, led to improvement of the obstruction and resolution of hemolysis. This case highlights the need to consider dynamic LVOTO in the differential diagnosis of post-SAVR hemolysis and to more aggressively evaluate the indication for concomitant septal myectomy in patients with preexisting hypertrophy.
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