Evidence map›Paper›PMID 40491617›Full record

ArticleCureus2025

Metastatic Oncocytic Renal Neoplasm Presenting as Gastrointestinal Bleeding.

Hasan Sqour, Abdul-Rahim Shilbayeh, Yasmin Gerais, Abdulrahman Sqour, Munther Hammad, Abdul-Rahman I Abusalim, Dolly Ewili, Marwah Alchalabi, Mohammad Salameh, Abdelfattah Saleh and 4 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hasan SqourInternal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Abdul-Rahim ShilbayehInternal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Yasmin GeraisGastroenterology, Saint Joseph Medical Center, Joliet, USA.
Abdulrahman SqourInternal Medicine, Yarmouk University, Irbid, JOR.
Munther HammadInternal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA.
Abdul-Rahman I AbusalimInternal Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA.
Dolly EwiliInternal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Marwah AlchalabiInternal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Mohammad SalamehInternal Medicine, Hamilton Medical Center, Dalton, USA.
Abdelfattah SalehInternal Medicine, Islamic Hospital, Amman, JOR.
Sammy HamadGastroenterology, Saint Joseph Medical Center, Joliet, USA.
Laura HamadGastroenterology, Saint Joseph Medical Center, Joliet, USA.
Fares HamadGastroenterology, Saint Joseph Medical Center, Joliet, USA.
Bachar HamadGastroenterology, Saint Joseph Medical Center, Joliet, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cancer (RC) is known for its diverse clinical presentations and unpredictable behavior. While it often metastasizes to common sites such as the lymph nodes, lungs, bones, and liver, its potential to metastasize to the gastrointestinal tract (GIT) is relatively rare. We report an unusual case of an 87-year-old male patient with a history of metastatic oncocytic renal neoplasm who presented with intermittent rectal bleeding. Colonoscopy revealed a bleeding mass in the sigmoid colon. Biopsy confirmed metastatic renal neoplasm, consistent with prior pathology. Immunohistochemistry was positive for AE1/AE3, CAIX, and PAX-8, supporting renal origin. Recent CT imaging showed enlargement of the left renal mass with direct extension into the descending colon and associated lymphadenopathy. Metastasis of RC in the GIT, especially the colon, is rare and even more so in oncocytic subtypes. This case underscores the importance of considering RC in patients with GI bleeding and a history of renal neoplasm. Early recognition and individualized, multidisciplinary management are crucial for optimal outcomes.

Indexed as

colon metastasisgastrointestinal bleedinggi bleedimmunotherapymetastatic renal canceroncocytic neoplasmrenal oncocytomasigmoid colon

Identifiers

PMID40491617
PMCPMC12146448

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.