Evidence map›Paper›PMID 40491580›Full record

ArticleToxicology reports2025

Maeve T Morris, Jordan L Pascoe, Jonathan T Busada

Abstract read
In one paragraph

Article in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Maeve T MorrisDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26505, USA.
Jordan L PascoeDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26505, USA.
Jonathan T BusadaDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26505, USA.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Karen H Martin · 2018 to 2026
$22.4M
COBRE Transitional Center in NeuroscienceP30GM103503 · NIGMS · WEST VIRGINIA UNIVERSITY · PI SPIROU, GEORGE A · 2012 to 2014
$3.2M
Pre-doctoral Training in Systems ToxicologyT32ES032920 · NIEHS · WEST VIRGINIA UNIVERSITY · PI Timothy R Nurkiewicz · 2022 to 2026
$1.2M
Cytek 3-laser AuroraS10OD028605 · OD · WEST VIRGINIA UNIVERSITY · PI BRUNDAGE, KATHLEEN M · 2021 to 2021
$259k
NIEHS NIH HHS T32 ES032920NIGMS NIH HHS P20 GM121322NIGMS NIH HHS P30 GM103503NIGMS NIH HHS U54 GM104942NIH HHS S10 OD028605
6 · The paper itself

Abstract

Glucocorticoids are steroid hormones that regulate stress homeostasis, metabolism, and inflammatory responses. Dysregulation of the glucocorticoid receptor (GR) is linked to diseases such as obesity, mood disorders, and immune dysfunction. Endocrine-disrupting chemicals (EDCs) are widespread environmental contaminants known to interfere with hormone signaling, but their impact on glucocorticoid signaling remains unclear. While several GR-disrupting compounds have been identified

Indexed as

DDTEndocrine Disrupting CompoundsGlucocorticoidsRU-486Ziram

Identifiers

PMID40491580
PMCPMC12148463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.