Evidence map›Paper›PMID 40491561›Full record

ArticleRegenerative therapy2025

Mapping intellectual structures and research hotspots of chronic wound in global perspective.

Yushu Zhu, Yizhen Lin, Sujie Xie, Mingxuan Yang, Wei Zhang, Minjuan Wu, Yifan Liu, Dayuan Xu, Shuyuan Xian, Xirui Tong and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Yushu ZhuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Yizhen LinNaval Medical University, Shanghai, 200025, China.
Sujie XieDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Mingxuan YangNaval Medical University, Shanghai, 200025, China.
Wei ZhangDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Minjuan WuDepartment of Histology and Embryology, Naval Military Medical University, Shanghai 200433, China.
Yifan LiuDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Dayuan XuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Shuyuan XianDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Xirui TongDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Jie HuangDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Luofeng JiangDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Xinya GuoDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Minyi GuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Hengkai YuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Xinran DingDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Yixu LiDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Yiyao DuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Heng HeDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Jianyu LuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Runzhi HuangDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Shizhao JiDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic wounds included but were not limited to diabetes foot ulcers, venous leg ulcers and pressure ulcers. The challenge of difficult healing placed a heavy burden on patients and society. Our objective was to explain the healing process of chronic wounds and the development of treatment technologies in the past few years and to provide relevant, valuable information. Methods: Our scientific publications were retrieved from the core collection of the Web of Science (WoSCC) database collection. The bibliometric visualization and analysis were performed by the software Biblioshiny based on R-bibliometrix. VOSviewer software and Citespace software were responsible for the validation of the results. Results: A total of 8129 articles related to wound healing in chronic wounds were retrieved. The countries, institutions, and journals with the highest number of publications were the USA, the N8 research partnership, and the Journal of Wound Care, respectively. Armstrong DG and Dumville JC were the most influential authors in this field. The keyword analysis showed two key clusters of keywords, including "dressings" and "management". Trend topics analysis revealed frequent keywords in recent years, including "nanofibers" and "injectable hydrogels". Conclusion: Our research was the first to reveal the cellular and molecular mechanisms and key clinical management strategies in the healing process of chronic wounds in the future through metrological and systematic evaluation, which may have important translational value in the future.

Indexed as

Chronic woundsDressingsHealingManagementNegative pressure wound therapy (NPWT)

Identifiers

PMID40491561
PMCPMC12146492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.