Evidence map›Paper›PMID 40491396›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Near-Infrared Afterglow Imaging-Guided Surgical Resection and Synergistic Photodynamic-Chemo Therapy of Breast Cancer.

Zixuan Li, Ranran Zhao, Qing Pei, Zhigang Xie, Min Zheng

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zixuan LiSchool of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, 2055 Yanan Street, Changchun, Jilin, 130012, P. R. China.
Ranran ZhaoSchool of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, 2055 Yanan Street, Changchun, Jilin, 130012, P. R. China.
Qing PeiKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
Zhigang XieKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
Min ZhengSchool of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, 2055 Yanan Street, Changchun, Jilin, 130012, P. R. China.ORCID https://orcid.org/0000-0002-4985-2680

Funding

National Natural Science Foundation of China 51873023Science and Technology Research Project of the Education Department of Jilin Province JJKH20250699KJ
6 · The paper itself

Abstract

The recurrence rate of cancer following surgical procedures is markedly affected by the degree of tumor removal. During the operation, tumor-targeted imaging is of crucial significance as it assists surgeons in attaining the most comprehensive tumor excision. Herein, a theranostic platform (CDSP NPs) is developed through the assembly of carbon dots (CDs) with paclitaxel prodrugs. CDSP NPs can be utilized for near-infrared (NIR) afterglow imaging-guided precise removal of breast cancer, featuring a long lifetime (>2 h), deep tissue penetration (>13 mm), and a high signal-to-noise ratio (SNR, 103.9), thereby effectively preventing cancer recurrence. Additionally, the combined treatment of photodynamic therapy (PDT) and chemotherapy substantially enhances tumor regression, demonstrating the tremendous potential of CDSP NPs for synergistic cancer treatment. This study proposes a straightforward but efficient model to build a nanoplatform integrating diagnosis and treatment, which is utilized for image-guided surgical navigation and effective tumor treatment.

Indexed as

Breast NeoplasmsPhotochemotherapySurgery, Computer-AssistedAnimalsAntineoplastic Agents, PhytogenicCell Line, TumorFemaleHumansLuminescent MeasurementsMiceMice, Inbred BALB CPaclitaxelTheranostic NanomedicineAntineoplastic Agents, PhytogenicPaclitaxelafterglowcarbon dots (CDs)imagingphotodynamic‐chemotherapysurgical resection

Identifiers

PMID40491396
PMCPMC12412500

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.