Evidence map›Paper›PMID 40491252›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Evaluating dietary quality and dietary inflammatory potential in cognitive impairment patients in China.

Dongsheng Bian, Furu Liang, Yong You, Xianfeng Li, Hua Hu, Huali Wang, Huayan Liu, Lu Shen, Oumei Cheng, Qiumin Qu and 23 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Evaluating dietary quality and dietary inflammatory potential in cognitive impairment patients in China.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Dongsheng BianDepartment of Neurology, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Furu LiangDepartment of Neurology, Baotou Central Hospital, Baotou, China.
Yong YouDepartment of Neurology, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Xianfeng LiDepartment of Neurology, Nanning First People's Hospital, the Fifth Affiliated Hospital of Guangxi Medical University, Nanning, China.
Hua HuDepartment of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Huali WangDementia Care and Research Center, Peking University Institute of Mental Health (Sixth Hospital), National Clinical Research Center for Mental Disorders (Peking University), Beijing, China.
Huayan LiuDepartment of Neurology, The First Hospital of China Medical University, Shenyang, China.
Lu ShenDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Oumei ChengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qiumin QuDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Shunliang XuDepartment of Neurology, The Second Hospital of Shandong University, Ji'nan, China.
Weihong KuangMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Qinying MaDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Xiaoping PanDepartment of Neurology, Guangzhou First People's Hospital, Guangzhou, China.
Xinyu ZhaoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yang ZhangYuyuan Community Health Service Center, Shanghai, China.
Yifeng DuDepartment of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Ying XuDepartment of Geriatric Cognitive Impairment, Zhongren Geriatric Nursing Hospital, Shanghai, China.
Yong'an SunDepartment of Neurology, Peking University First Hospital, Beijing, China.
Zhengluan LiaoDepartment of Psychiatry, Zhejiang Provincial People's Hospital, Hangzhou, China.
Jintao WangDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jianping LiDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jinwen XiaoDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haixia LiDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xinyi XieDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zike YunDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jieli GengDepartment of Neurology, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Wenwei CaoDepartment of Neurology, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Nan ZhiDepartment of Neurology, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Rujing RenDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hengge XieGeriatric Neurological Department of the Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Gang WangDepartment of Neurology, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
representing ADC

Funding

Brain Science and Brain-Like Intelligence TechnologyMinistry of Science and Technology of China 2021ZD0201804
6 · The paper itself

Abstract

introductionDiet plays a critical role in the prevention and treatment of cognitive impairment, yet dietary intake in patients with cognitive impairment in China remains insufficiently studied.

methodsA 25-item semi-quantitative food frequency questionnaire was used in a national online survey in China. The Dietary Inflammatory Index was calculated, and principal component analysis was used to identify dietary patterns.

resultsThe average daily energy intake was 1131.59 ± 486.30 kcal, below recommended levels. Patients in the pro-inflammatory diet group had lower intakes of nutrients than those in the anti-inflammatory group. Ordinal logistic regression indicated that adherence to a high-quality protein dietary pattern was associated with lower cognitive impairment severity, whereas the high cereal and snack dietary pattern was associated with increased severity.

conclusionInadequate intake of essential nutrients, particularly energy and protein, exacerbates cognitive decline. Promoting high-quality protein intake while reducing low-quality carbohydrates may mitigate cognitive deterioration and improve patient health outcomes. HIGHLIGHTS: Cognitive impairment patients in China show significantly low intake of energy, protein, and essential nutrients, which contributes to malnutrition and exacerbates cognitive decline. The study finds a link between inadequate nutrient intake and increased dietary inflammatory potential, which may accelerate cognitive decline. The pro-inflammatory deit with higher Dietary Inflammatory Index resulted from an overall insufficient intake of nutrients rather that the comsumption of excessively high levels of "pro-inflammatory" foods in patients. Dietary patterns with higher high-quality protein and lower low-quality carbohydrate intake may benefit nutritional status and cognitive health in cognitively impaired patients.

Indexed as

Cognitive DysfunctionDietInflammationAgedChinaEnergy IntakeFemaleHumansMaleMiddle AgedSurveys and Questionnairescognitive impairmentDietary Inflammatory Indexdietary patterndietary quality

Identifiers

PMID40491252
PMCPMC12149440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.