Evidence map›Paper›PMID 40491224›Full record

ArticleJournal of clinical ultrasound : JCU

Initial Evaluation of Lymphosonography to Identify Sentinel Lymph Nodes in Cervical and Vulvar Cancer Patients.

Priscilla Machado, Trang Vu, Norman Rosenblum, Aaron Shafer, Flemming Forsberg, Ji-Bin Liu

Abstract read
In one paragraph

Article in Journal of clinical ultrasound : JCU. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Priscilla MachadoDepartment of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-4107-2986
Trang VuDepartment of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Norman RosenblumDivision of Gynecological Oncology, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Aaron ShaferDivision of Gynecological Oncology, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Flemming ForsbergDepartment of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Ji-Bin LiuDepartment of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Funding

Detection of sentinel lymph nodes in female lower genital tract cancer patients with contrast-enhanced ultrasound imagingR21CA249870 · NCI · THOMAS JEFFERSON UNIVERSITY · PI LIU, JI-BIN · 2021 to 2022
$397k
NCI NIH HHS R21 CA249870NIH HHS
6 · The paper itself

Abstract

The objective of this pilot study was to identify sentinel lymph nodes (SLN) in cervical or vulvar cancer subjects scheduled for surgery using lymphosonography, comparing the findings with pathology. The contrast agent Sonazoid was administered subcutaneously around the tumor, and real-time contrast-enhanced ultrasound was performed to identify SLNs. Eleven SLNs were surgically excised, while lymphosonography identified 17 SLNs in 5 subjects. Comparing surgically excised SLNs and those identified by lymphosonography showed that 10 out of 11 SLNs (or 91%) were identified by lymphosonography. Lymphosonography identified all the benign SLNs and 2 out of the 3 malignant SLNs.

Indexed as

Lymph NodesSentinel Lymph NodeSentinel Lymph Node BiopsyUterine Cervical NeoplasmsVulvar NeoplasmsAdultAgedAged, 80 and overContrast MediaFemaleFerric CompoundsHumansIronLymphatic MetastasisMiddle AgedOxidesContrast MediaFerric CompoundsIronOxidesSonazoidcervical cancercontrast‐enhanced ultrasoundlymphatic mappinglymphosonographysentinel lymph nodeultrasound contrast agentvulvar cancer

Identifiers

PMID40491224
PMCPMC12354297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.