Evidence map›Paper›PMID 40491201›Full record

ReviewDrug delivery2025

Application of chitosan-based drug delivery systems in the treatment of bacterial diseases: a review.

Huan Huang, Yaxin Zhou, Jiehang Li, Zhijin Zhang, RongJia Han, Jingru Zuo, Yubin Bai, Jiyu Zhang

Abstract readReview
In one paragraph

Review in Drug delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huan HuangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Yaxin ZhouKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Jiehang LiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Zhijin ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
RongJia HanKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Jingru ZuoKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Yubin BaiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Jiyu ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial diseases are a significant challenge to human and animal health. The current treatment methods still have obvious shortcomings, such as poor targeting, low bioavailability, high side effects and drug resistance. Chitosan, with its outstanding biocompatibility, biodegradability, adhesiveness, antimicrobial properties, and ability to minimize drug side effects while improving bioavailability and therapeutic outcomes, serves as an ideal material for drug delivery systems, presenting a promising strategy for treating bacterial diseases. In this review, we briefly summarize the preparation methods of chitosan-based drug delivery systems and their application in the treatment of bacterial infections. The advantages of preparation of different types of chitosan-based drug delivery systems are discussed, supported by examples demonstrating their ability to improve drug antimicrobial activity, targeting, and bioavailability. Moreover, the current challenges, limitations, and future perspectives in this field were discussed, laying the groundwork for further development of chitosan-based drug delivery systems as high-performance and safe antimicrobial therapeutics.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsChitosanDrug Delivery SystemsAnimalsBiological AvailabilityDrug CarriersHumansAnti-Bacterial AgentsChitosanDrug Carriersbacterial diseaseChitosandrug delivery system

Identifiers

PMID40491201
PMCPMC12152997

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.