Evidence map›Paper›PMID 40491080›Full record

ArticleLupus2025

Diagnostic overshadowing in systemic lupus erythematosus (SLE): A qualitative study.

Rupert Harwood, Chris Wincup, David D'Cruz, Melanie Sloan

Abstract read
In one paragraph

Article in Lupus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rupert HarwoodSwansea University Medical School, Swansea, UK.ORCID 0009-0004-3831-7465
Chris WincupDepartment of Clinical and Academic Rheumatology, King's College Hospital, London, UK.
David D'CruzThe Louise Coote Lupus Unit, Guys' and St Thomas' Hospital, London, UK.
Melanie SloanDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesSLE diagnostic journeys can be protracted, with negative impacts on long-term health. This study explored the role of diagnostic overshadowing (DOS) in delaying SLE diagnoses.MethodsA qualitative analysis of 268 completed SLE patient surveys and 25 in-depth interviews purposively selected from the 2018-2021 Cambridge University Systemic Autoimmune Rheumatic Disease (SARD) studies.ResultsThe majority of participants appear to have experienced DOS and there were indications that sustained DOS (S-DOS) may add years to some SLE diagnostic journeys. Symptom misattributions which contributed to S-DOS included: (1) "

Indexed as

Delayed DiagnosisLupus Erythematosus, SystemicAdultAgedFemaleHumansInterviews as TopicMaleMiddle AgedQualitative ResearchSurveys and QuestionnairesYoung AdultattributionAutoimmunediagnostic overshadowinglupusmisdiagnosis

Identifiers

PMID40491080
PMCPMC12174620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.