ArticleJournal of oral rehabilitation2025
Association Between Cardiovascular Autonomic Function and Temporomandibular Disorders.
Article in Journal of oral rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Pain-Affective Disorder Comorbidity in the Temporomandibular Disorders: From Mechanistic Insights to Clinical Management.Neuroscience bulletin · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundStudies have shown that elevated stress levels associate with TMD-related pain, which suggests that alterations in autonomic tone may contribute to this pain condition.
objectiveThe aim of the study was to evaluate the sex-specific associations between autonomic nervous system (ANS) activity and TMD pain-related diagnoses in a population-based study.
methodsThe study was part of the Northern Finland Birth Cohort 1966. Of the cohort members, 1964 (62.3% of those invited to oral health examination) were clinically examined as part of the 46-year follow-up. ANS activity was assessed by means of heart rate variability (HRV) and baroreflex sensitivity (BRS). A total of 5 TMD diagnoses were based on the modified protocol of DC/TMD (Diagnostic Criteria for TMD). Of those, pain-related diagnoses, i.e., myalgia and arthralgia, were used. In logistic regression analyses stratified by sex assigned at birth, potential confounders, i.e., education, body mass index, and number of body pain sites, were considered.
resultsThose with TMD myalgia (n = 97) or arthralgia diagnoses (n = 102) had lower values of BRS while standing when adjusted for covariates among females (for myalgia OR 0.847, 95% Cl 0.744-0.964, p = 0.012) and for arthralgia (OR 0.871, 95% Cl 0.775-0.970, p = 0.021).
conclusionThe results suggest that lowered baroreflex sensitivity, indicating increased sympathetic tone, associates with TMD pain, at least to some extent, in females. These findings refer to the association of stress response with TMD.
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Registered trials
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