Evidence map›Paper›PMID 40490938›Full record

ArticleClinical and translational medicine2025

Imbalanced NK cell subpopulations and TIGIT expression limit cetuximab efficacy in colorectal cancer: A promising target for treatment enhancement.

Carmen Navarrete-Sirvent, Ana Mantrana, Aurora Rivas-Crespo, Alejandra Díaz-Chacón, Nerea M Herrera-Casanova, María Teresa Sánchez-Montero, Marta Toledano-Fonseca, María Victoria García-Ortiz, María José Ortiz-Morales, Gema Pulido and 7 more

Abstract read
In one paragraph

Article in Clinical and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Carmen Navarrete-SirventUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.ORCID https://orcid.org/0000-0002-8839-335X
Ana MantranaCentro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
Aurora Rivas-CrespoUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Alejandra Díaz-ChacónUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Nerea M Herrera-CasanovaUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
María Teresa Sánchez-MonteroUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Marta Toledano-FonsecaUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.ORCID https://orcid.org/0000-0002-1997-9197
María Victoria García-OrtizUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
María José Ortiz-MoralesDepartment of Medicine, Faculty of Medicine, University of Córdoba, Córdoba, Spain.
Gema PulidoDepartment of Medicine, Faculty of Medicine, University of Córdoba, Córdoba, Spain.
Mª Teresa CanoDepartment of Medicine, Faculty of Medicine, University of Córdoba, Córdoba, Spain.
Auxiliadora Gómez-EspañaDepartment of Medicine, Faculty of Medicine, University of Córdoba, Córdoba, Spain.
Rafael González-FernándezUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Lionel Le BourhisUniversité Paris Cité, INSERM U1160, Institut de Recherche Saint-Louis, Paris, France.
Silvia Guil-LunaUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.ORCID https://orcid.org/0000-0001-7542-3903
Antonio Rodríguez-ArizaUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.ORCID https://orcid.org/0000-0001-5304-5745
Enrique ArandaUniversity of Córdoba/Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.

Funding

Instituto de Salud Carlos III (ISCIII) PI20/00997Junta de AndalucíaNicolás MonardesThe European Union
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40490938
PMCPMC12148951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.