Evidence map›Paper›PMID 40490904›Full record

ArticleJournal of burn care & research : official publication of the American Burn Association2025

Using Cutaneous Functional Units (CFUs) to Understand Burn Characteristics Associated With Range of Motion at Hospital Discharge in Adult Burn Survivors.

Ingrid S Parry, Janice F Bell, Jeffrey C Schneider, Julie T Bidwell, Sheryl L Catz, Daniel J Tancredi

Abstract readMulticenter Study
In one paragraph

Article in Journal of burn care & research : official publication of the American Burn Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Cutaneous Functional Units Hierarchy, Version 2 Defined.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ingrid S ParryBetty Irene Moore School of Nursing, University of California, Davis, Davis, CA, United States.ORCID 0009-0007-7004-573X
Janice F BellBetty Irene Moore School of Nursing, University of California, Davis, Davis, CA, United States.ORCID 0000-0002-6528-0686
Jeffrey C SchneiderDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation, Harvard Medical School, Boston, MA, United States.ORCID 0000-0001-6652-7700
Julie T BidwellBetty Irene Moore School of Nursing, University of California, Davis, Davis, CA, United States.ORCID 0000-0003-3995-7689
Sheryl L CatzBetty Irene Moore School of Nursing, University of California, Davis, Davis, CA, United States.
Daniel J TancrediDepartment of Pediatrics, University of California, Davis, Davis, CA, United States.ORCID 0000-0002-3884-7907

Funding

ACL HHS 90DPBU0008
6 · The paper itself

Abstract

backgroundBurn injuries often lead to the development of burn scar contractures (BSC) and subsequent motion loss, which significantly impact function and quality of life for burn survivors. Understanding the relationship between burn characteristics and motion outcomes is critical to improving patient care and outcomes. We used a Cutaneous Functional Units (CFU) framework to investigate acute burn features at or near the time of injury associated with a joint-level range of motion at hospital discharge.

methodsThis study is an exploratory analysis of data collected as part of a previous prospective multicenter cohort study (N = 307 patients, 7441 joint motions). CFU features, including burn extent, skin grafting, burn location (proximal/ distal to joint crease), and adjacent CFU involvement, were evaluated while controlling for demographic and clinical variables. Fractional regression models evaluated associations between CFU burn features and range of motion.

resultsA higher percentage of CFU-burned and CFU-grafted, as well as advanced age, were significantly associated with reduced range of motion (P < .01). Burn extent in the proximal CFU areas also had a significant negative relationship with range of motion (P < .01). Total body surface area (TBSA) burned and TBSA-grafted were not associated with motion outcomes. Based on this exploratory analysis, a prediction model for BSC risk is proposed for further testing.

conclusionOur findings highlight the significance of burn characteristics within CFUs as key factors influencing motion outcomes. The CFU framework provides a standardized and functionally relevant approach to evaluating the localized impact of burn characteristics on joint motion, addressing a critical gap in the understanding of motion loss following burn injuries.

Indexed as

BurnsCicatrixContractureRange of Motion, ArticularAdultFemaleHumansMaleMiddle AgedPatient DischargeProspective StudiesSkin TransplantationSurvivorsburn scar contracturecutaneokinematicsCutaneous Functional Unitspredictionrange of motionrehabilitationscarring

Identifiers

PMID40490904
PMCPMC12292008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.