Evidence map›Paper›PMID 40490844›Full record

ArticleInfectious diseases of poverty2025

Babesia microti (Babesiidae, Piroplasmida) infection in a Chinese traveler returning from the United States of America.

Xin-An Huang, Rong Xiang, Ru-He Liao, Yu-Bo Luan, Yi-Lin Zhao, Ji-Hu Yang, Chun-Feng Luo, Lin Huang, Luo-Yuan Xia, Dai-Yun Zhu and 3 more

Abstract readCase Reports
In one paragraph

Article in Infectious diseases of poverty, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mapping the Global Distribution ofTransboundary and emerging diseases · 2025
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xin-An Huang *Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, People's Republic of China.
Rong Xiang *State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Ru-He Liao *Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, People's Republic of China.
Yu-Bo Luan *Internal Medicine, Beijing United Family Hospital, Beijing, 100015, People's Republic of China.
Yi-Lin ZhaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Ji-Hu YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Chun-Feng LuoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Lin HuangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Luo-Yuan XiaState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Dai-Yun ZhuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Yi SunState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, People's Republic of China.
Lei Wang *Beijing Institute of Tropical Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China. wangleibfh@ccmu.edu.cn.
Jia-Fu Jiang *Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, People's Republic of China. jiangjf2008@139.com.ORCID http://orcid.org/0000-0003-2624-7450

Funding

National Key Research and Development Program of China 2024YFC2607504
6 · The paper itself

Abstract

backgroundHuman babesiosis, caused by intraerythrocytic protozoa of the genus Babesia (Piroplasmida, Babesiidae), is a globally emerging zoonosis transmitted primarily through Ixodes spp. ticks. Babesia microti, which is endemic particularly in the northeastern and midwestern United States, accounts for the majority of globally reported human cases. Recent studies highlight its spread to non-traditional regions and cross-border transmission, driven by climate change, blood transfusions and increased human mobility. Despite increasing reports of autochthonous B. microti infections in certain areas of China, imported cases remain critically underrecognized due to overlapping clinical manifestations with malaria and limited diagnostic awareness. CASE PRESENTATION: We report a diagnostically challenging case of acute B. microti infection in a 52-year-old Chinese woman, presenting with a sudden recurrent fever (39.0-41.0 °C), hemolytic anemia (hemoglobin 104 g/L), thrombocytopenia (platelet 78 × 10

conclusionsThis study documented the first imported cases of human babesiosis in China, emphasizing the need for heightened clinical and public health vigilance. Screening travelers from endemic areas presenting with fever or hemolytic anemia for Babesia, bolstering molecular diagnosis, improving transfusion safety, and intensifying regional surveillance are crucial in reducing underdiagnosis and preventing transmission. These measures are essential for controlling babesiosis in China.

Indexed as

Babesia microtiBabesiosisChinaEast Asian PeopleFemaleHumansMiddle AgedTravelWisconsinBabesia microtiHemophagocytosisHuman babesiosisTravel-related diseases

Identifiers

PMID40490844
PMCPMC12150541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.