Observational studyEuropean journal of medical research2025
Severe thrombocytopenia is associated with adverse pregnancy outcomes in patients with obstetric antiphospholipid syndrome.
Observational study in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07757789 (Thrombocytopenia Trajectories as a Dynamic Biomarker of Clinical Severity and Survival in Antiphospholipid Syndrome), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thrombocytopenia Trajectories as a Dynamic Biomarker of Clinical Severity and Survival in Antiphospholipid Syndrome: A Multicenter Cohort Study
Who cites it
1 citing paper in PubMed.
- Current Approaches to the Management of Rheumatic Diseases in Pregnancy: Risk Stratification, Therapeutic Advances, and Maternal-Fetal Outcomes.Journal of personalized medicine · 2025Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThrombocytopenia is a common manifestation of antiphospholipid syndrome (APS). This study assesses the possible relationship between severe thrombocytopenia and adverse pregnancy outcomes (APOs) in obstetric APS (OAPS) patients.
methodsAn observational, cohort study was conducted at Peking University People's Hospital, Beijing, China. The demographic, clinical, immunologic, and pregnancy outcomes of the OAPS patients were collected. Univariate and multivariate logistic regression analyses were applied to assess the association between APOs and severe thrombocytopenia (< 30 × 10
resultsA total of 176 OAPS participants were included in the analysis, with 49 thrombocytopenia (< 100 × 10
conclusionThe risk of adverse pregnancy outcomes in patients with OAPS is contingent upon the severity of thrombocytopenia. Maintaining platelet counts above 50 × 10
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