Evidence map›Paper›PMID 40490782›Full record

ArticleBMC sports science, medicine & rehabilitation2025

Exercise interventions in patients with multiple myeloma: a scoping review.

Jiayao Li, Yi Peng, Di Zhan, Ying Zhang, Shanshan Yu

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07312942 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Adding a Controlled Breathing Protocol to a Therapeutic Exercise Program in Adults With Multiple Myeloma

TypeinterventionalSponsorUniversidad Complutense de MadridRan2026 to 2026Enrolled32ConditionsMultiple Myeloma, Breathing Techniques, Breathing Exercises, Exercise ActivityArmsControlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
NCT07376733 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of a Controlled Breathing and Therapeutic Exercise Program on Cardiorespiratory Variables in Patients With Multiple Myeloma

TypeinterventionalSponsorUniversidad Complutense de MadridRan2026 to 2026Enrolled26ConditionsMultiple Myeloma (MM), Breathing Techniques, Breathing Exercises, Exercise ActivityArmsControlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiayao LiHematology Department Nursing Platform, First Hospital of Jilin University, Xinmin Street, Changchun City, Jilin Province, 130021, China.
Yi PengHematology Department Nursing Platform, First Hospital of Jilin University, Xinmin Street, Changchun City, Jilin Province, 130021, China.
Di ZhanHematology Department Nursing Platform, First Hospital of Jilin University, Xinmin Street, Changchun City, Jilin Province, 130021, China.
Ying ZhangHematology Department Nursing Platform, First Hospital of Jilin University, Xinmin Street, Changchun City, Jilin Province, 130021, China.
Shanshan YuHematology Department Nursing Platform, First Hospital of Jilin University, Xinmin Street, Changchun City, Jilin Province, 130021, China. jinmaoer@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with multiple myeloma (MM) frequently experience impaired motor function and reduced quality of life. While exercise interventions play a vital role, no standardized guidelines tailored specifically to MM patients currently exist. This article reviews the scope of exercise interventions for patients with MM and further analyzes the current situation, providing references for early rehabilitation.

objectiveThis article aims to systematically analyze the application of exercise interventions in the rehabilitation of patients with MM, clarify the specific content, outcome indicators, and effects of exercise interventions, and provide relevant references for medical staff.

methodsUsing a scoping review methodology, we systematically conducted computerized searches across both Chinese (e.g., CNKI, Wanfang, Chinese Biomedical Literature Database) and international databases (e.g., Cochrane Library, PubMed, Embase) in accordance with the PRISMA-ScR checklist. The search timeframe encompassed records from database inception through 1 October 2024. Relevant literature meeting inclusion criteria underwent systematic summarization and critical analysis.

resultsA total of 17 studies were included, comprising 10 randomized controlled trials (RCTs), 4 single-arm trials, 1 retrospective cohort study, and 2 quasi-experimental studies‌. The types of exercise included aerobic exercise, resistance training, and Nordic walking (with a frequency of 3 to 5 times per week for 30 to 60 min each session).

conclusionAlthough existing studies exhibit inconsistencies in exercise types, parameters, supervision protocols, and limited evidence quality, our scoping review of relevant research findings demonstrates that exercise interventions positively improved fatigue levels, functional capacity, quality of life, and psychological well-being in patients with multiple myeloma (MM). This conclusion holds clinical relevance, as it not only addresses patients' concerns regarding exercise safety but also provides evidence-based guidance for healthcare professionals in developing personalized exercise plans tailored to patients at different treatment stages. Future research should prioritize establishing standardized, individualized exercise protocols based on patient profiles, particularly for those with bone metastases. REGISTRATION DETAILS: Open Science Framework ( https://doi.org/10.17605/OSF.IO/UDWM4 ).

Indexed as

Exercise effectExercise interventionsMotion evaluationMultiple myeloma

Identifiers

PMID40490782
PMCPMC12147358

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.