Evidence map›Paper›PMID 40490767›Full record

ArticleBMC veterinary research2025

In vitro assessment of lavender ethanolic extract supplemented semen extender on cryopreserved ram epididymal sperm quality and fertility outcome.

Ramin Farhadi, Amir Hossein Mohammadi Ghanatghestani, Roughayeh Abbasi, Dina Farshidfar, Abouzar Najafi

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Protective Effect ofAntioxidants (Basel, Switzerland) · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ramin FarhadiDepartment of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Amir Hossein Mohammadi GhanatghestaniDepartment of Animal and Poultry Sciences, Faculty of Agricultural Technologies, University of Tehran, Tehran, Iran.
Roughayeh AbbasiDepartment of Biological Sciences, Faculty of Basic Sciences, University of Shahid Madani Azerbaijan, Tabriz, Iran.
Dina FarshidfarDepartment of Animal and Poultry Sciences, Faculty of Agricultural Technologies, University of Tehran, Tehran, Iran.
Abouzar NajafiDepartment of Animal and Poultry Sciences, Faculty of Agricultural Technologies, University of Tehran, Tehran, Iran. abozar.najafi@ut.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the protective role of different concentrations of lavender ethanolic extract (0, 75, 150, and 300 μg/dL) on the microscopic, oxidative stress, structural, and fertility parameters of ram epididymal sperm after the freezing/thawing process. Post-thaw evaluations included motility parameters, membrane integrity, acrosome membrane integrity, abnormality, MDA concentration, superoxide dismutase and glutathione peroxidase enzyme activities, viability, apoptosis stages, mitochondrial membrane potential, DNA fragmentation, ROS levels, and fertility parameters (pregnancy rate, birth rate, and lambing rate). The results indicated that the extender containing 150 µg/dL lavender extract improved motility parameters, including progressive motility and VCL compared to the control extender. In the evaluation of structural and biochemical parameters, the addition of 150 µg/dL lavender extract significantly enhanced plasma membrane and acrosome integrity, as well as superoxide dismutase activity, while reducing sperm abnormalities and MDA concentration compared to the control group. There was no significant difference in glutathione peroxidase activity between different extract concentrations. Furthermore, the presence of 150 µg/dL lavender extract increased mitochondrial membrane potential and sperm viability, while significantly decreasing H

Indexed as

CryopreservationCryoprotective AgentsLavandulaPlant ExtractsSemen PreservationSpermatozoaAnimalsDNA FragmentationEpididymisEthanolFemaleFertilityMalePregnancySemen AnalysisSheepCryoprotective AgentsEthanolPlant ExtractsAntioxidantExtractLavenderOxidative stressSperm

Identifiers

PMID40490767
PMCPMC12147334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.