Evidence map›Paper›PMID 40490711›Full record

ArticleACS biomaterials science & engineering2025

Optimizing Isolation Methods and Exploring the Therapeutic Potential of Lotus-Derived Extracellular Vesicles in Modulating Inflammation and Promoting Wound Healing.

Kai-Jiun Lo, Mu-Hui Wang, Ching-Yao Kuo, Min-Hsiung Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kai-Jiun LoInstitute of Food Science and Technology, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0001-8142-2077
Mu-Hui WangDepartment of Medical Research, National Taiwan University Hospital, Taipei 100225, Taiwan.
Ching-Yao KuoBO HUI BIOTECH CO., LTD., New Taipei City 248016, Taiwan.
Min-Hsiung PanInstitute of Food Science and Technology, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0002-5188-7030

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decade, with the rise of research on plant-derived extracellular vesicles (PDEVs), scientists have been continuously exploring the bioactivity of PDEVs. Many PDEVs have been shown to possess a variety of biological activities. Given that the specific characteristics of EVs are believed to be related to their source cells, PDEVs from traditional Chinese medicinal herbs hold significant potential for development. In this study, lotus (

Indexed as

Extracellular VesiclesInflammationLotusNelumboWound HealingAnimalsCell MovementHumansMicePlant LeavesRAW 264.7 Cellsanti-inflammationlotus-derived extracellular vesiclesNelumbo nuciferatangential flow filtrationwound healing

Identifiers

PMID40490711
PMCPMC12264863

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.