ArticleBMC pulmonary medicine2025
The clinical usefulness of neutrophil percentage/albumin ratio in predicting the one-month mortality in chronic obstructive pulmonary disease patients hospitalized with community-acquired pneumonia.
Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of sex on the association between neutrophil percentage-to-albumin ratio and mortality in perioperative patients with chronic kidney disease: a retrospective analysis of the INSPIRE database.Perioperative medicine (London, England) · 2026Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCommunity-acquired pneumonia (CAP) is a significant cause of hospitalization in chronic obstructive pulmonary disease (COPD), negatively impacting both morbidity and mortality. The neutrophil percentage-to-albumin ratio (NPAR) is a recently introduced indicator combining systemic inflammation and nutritional status. This study aimed to clarify the prognostic significance of NPAR in predicting one-month mortality among COPD patients hospitalized with CAP.
methodsMedical records of the study population between January 1, 2014, and December 31, 2020, were retrospectively reviewed. NPAR values at admission were calculated. The Cox proportional hazards model was used to investigate the association between the NPAR, log NPAR, and one-month mortality. Receiver operating characteristic (ROC) analysis was performed to compare the predictive value of log NPAR with established clinical scoring systems.
resultsA total of 508 patients were included in the study. Higher NPAR and log NPAR were significantly associated with one-month mortality in Cox analysis after adjustment for age and gender (HR:2.175, p:0.01 and HR:6.853, p:0.031). However, after adjusting for additional confounding factors, NPAR and long NPAR were no longer significantly associated with one-month mortality. ROC analysis demonstrated that log NPAR had a superior predictive value for one-month mortality compared to PSI and CURB-65 scores (AUC for log NPAR: 0.654, for PSI: 0.596, and CURB-65: 0.569, p:0.005). Furthermore, higher NPAR was associated with disease severity, prolonged hospital stays, and treatment-related mortality (all p < 0.05).
conclusionsNPAR may be a useful biomarker for assessing one-month mortality, disease severity, and treatment outcomes in COPD patients with CAP. Further research is needed to determine its role in guiding therapeutic decisions.
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