ArticleBMC neurology2025
A four-year assessment of demographic information, clinical presentations, risk factors and outcomes in lacunar stroke patients.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Machine learning-based identification of concomitant stroke and prognostic analysis in patients with Guillain-Barré syndrome: a retrospective study.Frontiers in immunology · 2026Article
- Association Between TSH Level and Stroke Severity: A Cross-Sectional Study Using the mRS.Stroke research and treatment · 2025Article
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8 authors.
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Abstract
backgroundStroke, the second leading cause of global death, includes ischemic strokes, which account for 71% of cases. Lacunar infarcts, small ischemic lesions due to small vessel occlusion, represent about 25% of ischemic strokes. This study investigates the demographic, clinical characteristics, and outcomes of lacunar stroke patients in Tabriz, Iran, where such data are limited.
methodsThis cross-sectional study utilized data from 251 patients with acute lacunar stroke, collected from the Neuroscience Research Center (NSRC) registry at Tabriz University of Medical Sciences, covering January 2019 to January 2023. Diagnosis was confirmed using FLAIR and DW-MRI, with lacunar infarcts defined per STRIVE criteria. Functional outcomes were measured using the modified Rankin Scale (mRS) at admission, discharge, and 90 days post-stroke. Data were analyzed using SPSS version 27.
resultsThe cohort had a median age of 60 years, with 159 males and 92 females. Hypertension (70.1%) and diabetes mellitus (37.1%) were the most common risk factors. Dysarthria (53.8%) and motor deficits (right upper limb 43.8%, lower limb 41.8%) were prevalent. Pre-stroke mRS scores showed no disability in 80.88% of patients. By discharge, most had mRS scores of 1 or 2. At 90 days, 27.49% had fully recovered. The 90-day case fatality rate was 3.19%, with 3.2% experiencing complications.
conclusionsHypertension and diabetes mellitus are critical risk factors for lacunar stroke. The study indicates generally favorable outcomes with appropriate management. Findings highlight the need for ongoing risk factor control and suggest further multicenter studies to validate results and explore long-term outcomes.
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