Evidence map›Paper›PMID 40490621›Full record

ArticleImmunologic research2025

Deucravacitinib as a monotherapy for concurrent management of psoriasis and chronic spontaneous urticaria.

Xiaoying Zhang, Chenxi Zhang, Jiali Liang, Yifei Liu, Bichun Xu, Changxing Li

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Immunologic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoying ZhangDepartment of Dermatology, the Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Southern Medical University, Dongguan, China.
Chenxi ZhangDepartment of Dermatology, the Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Southern Medical University, Dongguan, China.
Jiali LiangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yifei LiuDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Bichun XuDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Changxing LiDepartment of Dermatology, the Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Southern Medical University, Dongguan, China. lilichangxing@163.com.

Funding

the National Natural Science Foundation of China NSFC 82173437 and 82473543
6 · The paper itself

Abstract

Patients with autoimmune diseases are susceptible to developing a second autoimmune disorder. Psoriasis, a common autoimmune disease, frequently occurs alongside other autoimmune conditions in some individuals. We report the case of a young female patient diagnosed with plaque psoriasis, initially treated with secukinumab, and achieved complete skin clearance at 12 weeks. However, she experienced a decline in the efficacy of secukinumab, with recurrence of symptoms and subsequent development of chronic spontaneous urticaria (CSU) and was switched to treatment with deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor. The use of deucravacitinib resulted in a favorable therapeutic outcome, effectively managing both psoriasis and CSU 12 weeks after treatment. This case highlights the potential of deucravacitinib as a novel monotherapy for patients with both psoriasis and CSU.

Indexed as

Chronic UrticariaProtein Kinase InhibitorsPsoriasisFemaleHumansTreatment OutcomeYoung AdultProtein Kinase InhibitorsChronic spontaneous urticaria (CSU)DeucravacitinibMonotherapyPsoriasis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.