Evidence map›Paper›PMID 40490577›Full record

ArticleSurgical endoscopy2025

Does the use of EndoFLIP during fundoplications improve outcomes?

Andrew F Sabour, Emily D Duckworth, Marvin A Rhodes, Dawn W Blackhurst, Erica Schumann, Shanu N Kothari, Brian Hodgens

Abstract read
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew F SabourDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US. afsabour@gmail.com.ORCID http://orcid.org/0000-0001-7817-6506
Emily D DuckworthDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.
Marvin A RhodesDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.
Dawn W BlackhurstDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.
Erica SchumannDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.
Shanu N KothariDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.
Brian HodgensDivision of Surgery, Department of Surgery, Prisma Health/USC School of Medicine Greenville, 905 Verdae Blvd, Suit #202, Greenville, SC, 29607, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImpedance planimetry (EndoFLIP) provides a powerful intraoperative tool to the trained Foregut surgeon. Real time data on esophageal diameter and distensibility index (DI) allows for objective biofeedback to improve the overall consistency of the operation. While EndoFLIP carries great potential, little has been said about its effect toward postoperative outcomes. Our goal for this study was to identify how certain EndoFLIP scores would impact postoperative patient surveys.

methodsA prospectively collected database of patients undergoing crural repair between January 2023 and September 2024 was reviewed. EndoFLIP measurements of DI and diameter were obtained after fundoplication using a standardized protocol. Patients were then surveyed postoperatively at 2 months, 6 months, and 1-year intervals to trend changes in GERD-HRQL, REGURG, LPR-RSI, and Dysphagia scores. Spearman Rank correlation was used to assess linear relationships between post-fundoplication measurements and quality-of-life scores at follow up.

resultsA total of 55 patients were reviewed in this study. All patients underwent a crural repair while 45% underwent an anterior wrap and 55% a posterior wrap. Diameter and DI measurements were not found to correlate with GERD-HRQL or LPR-RSI scores at 1-year postoperative visits. No correlation was also found when looking at the change in scores from preoperative to postoperative surveys. Larger DI and diameters did correlate to higher REGURG scores at 1-year follow ups.

conclusionsIntraoperative DI and diameter measurements carry almost no correlation to postoperative outcome scores. Only a positive correlation to REGURG scores with higher DI and diameter were noted. As long as DI is kept between extreme values, other factors must be investigated as part of a multifactorial influence to postoperative dysphagia and GERD.

Indexed as

Electric ImpedanceEsophagusFundoplicationGastroesophageal RefluxAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesQuality of LifeTreatment OutcomeDistensibilityEndoFLIPForegutFundoplicationHiatal herniaPlanimetry

Identifiers

PMID40490577
PMCPMC12222382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.