Evidence map›Paper›PMID 40490570›Full record

ArticleBrain informatics2025

AI-driven multi-agent reinforcement learning framework for real-time monitoring of physiological signals in stress and depression contexts.

Thanveer Shaik, Xiaohui Tao, Lin Li, Haoran Xie, Hong-Ning Dai, Feng Zhao, Jianming Yong

Abstract read
In one paragraph

Article in Brain informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thanveer ShaikSchool of Mathematics, Physics & Computing, University of Southern Queensland, Toowoomba, Australia. Thanveer.Shaik@unisq.edu.au.
Xiaohui Tao *School of Mathematics, Physics & Computing, University of Southern Queensland, Toowoomba, Australia.
Lin Li *School of Computer and Artificial Intelligence, Wuhan University of Technology, Wuhan , China.
Haoran Xie *Division of Artificial Intelligence, School of Data Science, Lingnan University, Hong Kong , China.
Hong-Ning Dai *Department of Computer Science, Hong Kong Baptist University, Hong Kong, China.
Feng Zhao *Huazhong University of Science and Technology, Wuhan , China.
Jianming Yong *School of Business, University of Southern Queensland, Toowoomba, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEffective patient monitoring is crucial for timely healthcare interventions and improved outcomes, especially in managing conditions influenced by stress and depression, which can manifest through physiological changes. Traditional monitoring systems often struggle with the complexity and dynamic nature of such conditions, leading to delays in identifying critical scenarios. This study proposes a novel multi-agent deep reinforcement learning (DRL) framework to address these challenges by monitoring vital signs and providing real-time decision-making capabilities.

methodsOur framework deploys multiple learning agents, each dedicated to monitoring specific physiological features such as heart rate, respiration, and temperature. These agents interact with a generic healthcare monitoring environment, learn patients' behavior patterns, and estimate the level of emergency to alert Medical Emergency Teams (METs) accordingly. The study evaluates the proposed system using two real-world datasets-PPG-DaLiA and WESAD-designed to capture physiological and stress-related data. The performance is compared with baseline models, including Q-Learning, PPO, Actor-Critic, Double DQN, and DDPG, as well as existing monitoring frameworks like WISEML and CA-MAQL. Hyperparameter optimization is also performed to fine-tune learning rates and discount factors.

resultsExperimental results demonstrate that the proposed multi-agent DRL framework outperforms baseline models in accurately monitoring patients' vital signs under stress and varying conditions. The optimized agents adapt effectively to dynamic environments, ensuring timely detection of critical health deviations. Comparative evaluations reveal superior performance in metrics related to decision-making accuracy and response efficiency, highlighting the robustness of the framework.

conclusionsThe proposed AI-driven monitoring system offers significant advancements over traditional methods by handling complex and uncertain environments, adapting to varying patient conditions influenced by stress and depression, and making autonomous, real-time decisions. While the framework demonstrates high accuracy and adaptability, challenges related to data scale and future vital sign prediction remain. Future research will focus on extending predictive capabilities to further enhance proactive healthcare interventions.

Indexed as

Behavior patternsDecision makingPatient monitoringReinforcement learningVital signs

Identifiers

PMID40490570
PMCPMC12149378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.