Evidence map›Paper›PMID 40490561›Full record

ArticleDiscover oncology2025

The impact of the COVID-19 pandemic on the small cell lung cancer epidemiology.

Xuemei Zhang, Lele Chang, Wansu Xu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xuemei Zhang *Department of Radiation Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, RD. Minjiang, Dist. Kecheng, Quzhou, Zhejiang, China.
Lele Chang *Departments of Gynecology, Fujian Cancer Hospital and Fujian Medical University Cancer Hospital, Fujian Medical University, Fuzhou, China.
Wansu XuDepartment of Radiation Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, RD. Minjiang, Dist. Kecheng, Quzhou, Zhejiang, China. xws198712@126.com.ORCID http://orcid.org/0009-0003-5419-9879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the potential impact of the coronavirus disease 2019 (COVID-19) pandemic on the epidemiology of small-cell lung cancer (SCLC).

methodsSCLC patients were collected from the Surveillance, Epidemiology, and End-Results (SEER) database (diagnosed between 2018 and 2021) and grouped according to the timing of the COVID-19 pandemic. Intergroup comparisons and survival analyses were performed on clinicopathologic characteristics and survival data to explore the differences in morbidity characteristics and survival in SCLC patients before and after the pandemic.

resultsSCLC Patients diagnosed in the post-COVID-19 pandemic tended to have earlier tumor stage, receive chemotherapy (OR 1.14, 95% CI 1.02-1.27, P-value = 0.02) rather than radiotherapy (OR 0.89, 95% CI 0.84-0.96, P-value < 0.01), and have increased time to treatment delay. Balancing follow-up time and constructing improved survival curves, patients with SCLC diagnosed after the pandemic tended to have a worse prognosis.

conclusionsDifferences in some clinicopathologic factors and treatment choices, or the pandemic itself, may result in a tendency for patients with SCLC diagnosed after the pandemic to have a worse prognosis, alerting clinicians to the need to focus on the management and treatment of this population.

Indexed as

COVID-19DiagnosisPrognosisRadiotherapySmall cell lung cancer

Identifiers

PMID40490561
PMCPMC12149354

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.