Improved ESI-MS Sensitivity via an Imidazolium Tag (DAPMI-ITag) for Precise Sialic Acid Detection in Human Serum and CMAH-Null Mouse Tissues.

Yao-Yao Zhang, Zi-Xuan Hu, Si-Yu Zhang, Li Liu, M Carmen Galan, Josef Voglmeir, Mattia Ghirardello

Abstract read

In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yao-Yao ZhangGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.

Zi-Xuan HuGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.

Si-Yu ZhangGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.

Li LiuGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.ORCID 0000-0002-2178-9237

M Carmen GalanSchool of Chemistry, University of Bristol, Cantock's Close, BS8 1TS Bristol, U.K.

Josef VoglmeirGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.ORCID 0000-0002-4096-4926

Mattia GhirardelloSchool of Chemistry, University of Bristol, Cantock's Close, BS8 1TS Bristol, U.K.ORCID 0000-0002-2855-4801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialic acids (Sias), consisting primarily of

Indexed as

ImidazolesN-Acetylneuraminic AcidSpectrometry, Mass, Electrospray IonizationAnimalsHumansLimit of DetectionMiceMice, KnockoutMixed Function OxygenasesNeuraminic AcidsCMPacetylneuraminate monooxygenaseImidazolesMixed Function OxygenasesN-Acetylneuraminic AcidNeuraminic AcidsN-glycolylneuraminic acid

Identifiers

PMID40490447

DOI10.1021/acs.analchem.5c00752

PMCPMC12199228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.