Evidence map›Paper›PMID 40490382›Full record

ArticleInfection & chemotherapy2025

Antimicrobial Prescribing Patterns in Russian Outpatients in 2024: Results of the Global-PPS Project.

Svetlana Rachina, Yuliya Belkova, Roman Kozlov, Anastasia Kurkova, Annelies Boven, Ann Versporten, Ines Pauwels, Erika Vlieghe, Aleksandr Stafeev, Sergey Zyryanov and 14 more

Abstract read
In one paragraph

Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Svetlana RachinaDepartment of Hospital Therapy #2, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-3329-7846
Yuliya BelkovaDepartment of Clinical Pharmacology, Smolensk State Medical University, Smolensk, Russian Federation. Yuliya.belkova@antibiotic.ru.ORCID https://orcid.org/0000-0002-4422-6517
Roman KozlovInstitute of Antimicrobial Chemotherapy, Smolensk State Medical University, Smolensk, Russian Federation.ORCID https://orcid.org/0000-0001-8728-1113
Anastasia KurkovaInstitute of Antimicrobial Chemotherapy, Smolensk State Medical University, Smolensk, Russian Federation.ORCID https://orcid.org/0000-0002-0076-8795
Annelies BovenGlobal Health Institute, University of Antwerp, Antwerp, Belgium.ORCID https://orcid.org/0000-0003-0713-7491
Ann VersportenGlobal Health Institute, University of Antwerp, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-3551-6643
Ines PauwelsGlobal Health Institute, University of Antwerp, Antwerp, Belgium.ORCID https://orcid.org/0000-0003-0106-2118
Erika VliegheGlobal Health Institute, University of Antwerp, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-4865-3030
Aleksandr StafeevDepartment of Hospital Therapy #2, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.ORCID https://orcid.org/0000-0001-9350-968X
Sergey ZyryanovDepartment of General and Clinical Pharmacology, RUDN University, Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-6348-6867
Veriko KukavaN.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-3687-2439
Elena BochanovaDepartment of Microbiology named after Associate Professor B.M. Zelmanovich, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation.ORCID https://orcid.org/0000-0003-4371-2342
Ekaterina EliseevaDepartment of General and Clinical Pharmacology, Pacific State Medical University, Vladivostok, Russian Federation.ORCID https://orcid.org/0000-0001-6126-1253
Galina KetovaDepartment of Outpatient therapy and Clinical Pharmacology, South Ural State Medical University, Chelyabinsk, Russian Federation.ORCID https://orcid.org/0000-0001-5087-9525
Elena LuchshevaOutpatient Hospital #1, Kuzbass Children's Clinical Hospital named after Prof. Yu.E. Malakhovsky, Novokuznetsk, Russian Federation.ORCID https://orcid.org/0009-0002-7715-2144
Shamil PalyutinDepartment of Clinical Pharmacology, Yaroslavl State Medical University, Yaroslavl, Russian Federation.ORCID https://orcid.org/0000-0002-0501-4853
Irina PanshinaChildren's City Clinical Hospital #11, Children's City Clinical Hospital No. 11, Ekaterinburg, Russian Federation.ORCID https://orcid.org/0000-0001-7529-0047
Ulyana PortnyaginaDepartment of Internal Medicine and General Practice (Family Medicine), North-Easten Federal University, Yakutsk, Russian Federation.ORCID https://orcid.org/0000-0003-2791-9933
Olga ReshetkoDepartment of Pharmacology, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation.ORCID https://orcid.org/0000-0003-3107-7636
Vera ShegimovaDepartment of Clinical Pharmacology, Republican Clinical Hospital named after N.A. Semashko, Ulan-Ude, Russian Federation.
Mikhail ShutovCity Outpatient Hospital #64, Moscow, Russian Federation.ORCID https://orcid.org/0009-0009-0530-5034
Natalya TitovaDepartment of General Practice, Outpatient Therapy with Postgraduate Geriatrics Education, Smolensk State Medical University, Smolensk, Russian Federation.ORCID https://orcid.org/0000-0003-2591-1890
Sergey YakushinDepartment of Outpatient Paediatrics, Smolensk State Medical University, Smolensk, Russian Federation.ORCID https://orcid.org/0000-0003-2564-4980
Russian Global-PPS Project Study Group

Funding

Universiteit Antwerpen
6 · The paper itself

Abstract

backgroundDetailed surveillance of antimicrobials' use in the community is an essential strategy to control their overuse and misuse. This study aimed to evaluate prescribing patterns of antimicrobials in Russian outpatients in 2024 and quantify the prescribing in relation to quality indicators. MATERIALS AND

methodsA point prevalence study was conducted during January-April 2024 in 14 healthcare facilities in 11 Russian cities (Chelyabinsk, Ekaterinburg, Krasnoyarsk, Moscow, Novokuznetsk, Saratov, Smolensk, Ulan-Ude, Vladivostok, Yakutsk, and Yaroslavl) in accordance with the outpatient protocol of Global-PPS project. Detailed data on antimicrobials, age, gender, and drug indications were collected for each outpatient receiving at least one agent for prophylaxis or treatment.

resultsA total of 5,084 outpatients from 149 units were surveyed, of which 487 (9.6%) received at least one antimicrobial agent. The highest rates of antimicrobial prescribing were observed at upper respiratory tract (33.2%), gastroenterology (22.6%), hematology (13.6%), ear nose and throat (13.5%), and gynecology units (11.6%). Antibacterials accounted for 63.4% of antimicrobials on average, followed by antivirals (35.4%). Penicillins (41.4%), for the most part penicillin/beta-lactamase inhibitor combinations (30.1%), cephalosporins (18.3%), including third generation (17.7%), fluoroquinolones (16.1%), and macrolides (11.5%) were the top classes of antibiotics prescribed. Umifenovir (23.8%) and amoxicillin/clavulanic acid (19.0%) were the top antimicrobials prescribed. The administered antibacterials were almost equally distributed between "access" (46.5%) and "watch" (53.5%) AWaRe groups. On average, choice of antimicrobials followed the national guidelines issued by the Ministry of Health in 73.2% of cases.

conclusionThe pooled rates of antimicrobial prescribing in outpatient settings was 9.6% with the substantial differences in patterns of consumption overall and among the units of different types. Broad-spectrum antibacterials such as penicillin/beta-lactamase inhibitor combinations, III-IV generation cephalosporins, fluoroquinolones, and macrolides together amounted to 48% of prescriptions. Common concerns in antimicrobial drug usage included low guidelines compliance and low rate of "access" group antibacterials.

Indexed as

AntibioticAntimicrobialAntiviralOutpatientsQuality indicator

Identifiers

PMID40490382
PMCPMC12230390

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.