Evidence map›Paper›PMID 40490298›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)

Robust renewal after extinction of remotely acquired Pavlovian conditioning.

Joseph W Charles, Samantha K Moriarty, Danielle I Fournier, Neil E Winterbauer, Emily A Cooper, Travis P Todd

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph W CharlesDepartment of Psychological Science, University of Vermont, Burlington, Vermont 05405, USA.
Samantha K MoriartyDepartment of Psychological Science, University of Vermont, Burlington, Vermont 05405, USA.
Danielle I FournierDepartment of Psychological Science, University of Vermont, Burlington, Vermont 05405, USA.
Neil E WinterbauerDepartment of Psychological Science, University of Vermont, Burlington, Vermont 05405, USA.
Emily A CooperHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, California 94720, USA.
Travis P ToddDepartment of Psychological Science, University of Vermont, Burlington, Vermont 05405, USA travis.todd@uvm.edu.

Funding

Cortical circuitry and mechanisms underlying remote cue-specific fear memory and extinctionR01MH118734 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI GULLEDGE, ALLAN T, SMITH, KYLE S · 2019 to 2023
$2.4M
NIMH NIH HHS R01 MH118734
6 · The paper itself

Abstract

Extinguished responses are prone to renew outside the context where extinction occurred. Two experiments compared extinction and renewal following either a 1 day conditioning-to-extinction interval or a 27 day interval. Rats received tone-shock pairings in Context A, and extinction in Context B. Testing occurred in Context A (Experiment 1) or C (Experiment 2). Extinction occurred at a similar rate after both retention intervals. Robust renewal was also observed and was not affected by the conditioning-to-extinction retention interval. Results are discussed with respect to prior research on the timing of extinction, the neurobiology of recent and remote memory retrieval, and translational relevance.

Indexed as

Conditioning, ClassicalExtinction, PsychologicalAcoustic StimulationAnimalsElectroshockMaleRatsRats, Long-EvansRats, Sprague-DawleyTime Factors

Identifiers

PMID40490298
PMCPMC12177356

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.