Evidence map›Paper›PMID 40490224›Full record

SynthesisJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2025

Multimodality Imaging in Presurgical Evaluation of Total Anomalous Pulmonary Venous Connection: Single-Center Practice Variability and a Systematic Review of Diagnostic Error.

Helen M Stanley, Danish Vaiyani, Meryl S Cohen, Shobha S Natarajan, Brian R White

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Echocardiography-Assisted Stenting of the Ductus Venosus in Infracardiac TAPVC: Report of a New Technique and Review of the Literature.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Helen M StanleyDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: stanleyh1@chop.edu.
Danish VaiyaniDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Meryl S CohenDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Shobha S NatarajanDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Brian R WhiteDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Funding

Optical Functional Neuroimaging of Acute and Chronic HypoxiaK08NS117897 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI WHITE, BRIAN RICHARD · 2020 to 2024
$843k
NINDS NIH HHS K08 NS117897
6 · The paper itself

Abstract

backgroundPulmonary vein anatomy varies widely in total anomalous pulmonary venous connection (TAPVC), with diagnostic accuracy affecting surgical planning and prognosis. Echocardiography is the preferred screening modality. Cross-sectional imaging (cardiac computed tomography [CT] or magnetic resonance [MR]) may offer added value.

methodsAs the first step in a quality improvement initiative, we sought to describe practice patterns in presurgical imaging in TAPVC with attention to diagnostic error. We also evaluated the available literature on diagnostic accuracy of imaging in TAPVC. Patients with TAPVC who underwent repair at our center (January 1, 2006, to September 15, 2022) were included.

resultsThirty-three of 167 patients (20%) underwent presurgical CT or MR. Initial echocardiogram incorrectly diagnosed the subtype of TAPVC in 9% (15/167). Patients with birth weight under 3 kg, born preterm, or with an initial diagnosis of mixed-type TAPVC were more likely to have misdiagnosis by initial echocardiogram. Computed tomography or MR miscategorized 3/33 patients. A systematic literature review revealed 10 studies that evaluated CT imaging diagnostic accuracy in TAPVC, one of which also included MR studies. Among 171 total patients, there were no patients with inaccurate anatomic diagnosis by CT or MR.

conclusionsCross-sectional angiography is used increasingly in this population and with diagnostic excellence, although it is not infallible. Efforts to improve echocardiographic quality as well as multimodality imaging in high-risk patients may improve diagnostic accuracy and surgical planning.

Indexed as

Diagnostic ErrorsEchocardiographyMagnetic Resonance ImagingMultimodal ImagingPreoperative CarePulmonary VeinsScimitar SyndromeTomography, X-Ray ComputedFemaleHumansInfantInfant, NewbornMaleReproducibility of ResultsComputed tomographyCongenital heart diseaseMagnetic resonanceMultimodality imagingPediatric cardiologypulmonary venous anomalies

Identifiers

PMID40490224
PMCPMC12354200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.