Evidence map›Paper›PMID 40490190›Full record

Trial reportAcademic pediatrics

Impact of Interventions to Improve Human Papillomavirus Vaccine Uptake on Other Vaccines Due: A Secondary Analysis of a Randomized Trial.

Robert M Jacobson, Jeph Herrin, Gregory Jenkins, Joan M Griffin, Jennifer L St Sauver, Kathy L MacLaughlin, Xuan Zhu, Lila J Finney Rutten

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert M JacobsonDivision of Community Pediatric and Adolescent Medicine (RM Jacobson), Mayo Clinic, Rochester, Minn; Division of Pediatric Infectious Diseases (RM Jacobson), Mayo Clinic, Rochester, Minn; Division of Epidemiology (RM Jacobson, JL St. Sauver, LJ Finney Rutten), Mayo Clinic, Rochester, Minn. Electronic address: jacobson.robert@mayo.edu.
Jeph HerrinSection of Cardiovascular Medicine (J Herrin), Yale University School of Medicine, New Haven, Conn; Flying Buttress Associates (J Herrin), Charlottesville, Va.
Gregory JenkinsDivision of Biomedical Statistics and Informatics (G Jenkins), Mayo Clinic, Rochester, Minn.
Joan M GriffinDivision of Health Care Delivery Research and the Robert D. and Patricia E. Kern Center for Science of Health Care Delivery (JM Griffin), Mayo Clinic, Rochester, Minn.
Jennifer L St SauverDivision of Epidemiology (RM Jacobson, JL St. Sauver, LJ Finney Rutten), Mayo Clinic, Rochester, Minn.
Kathy L MacLaughlinDepartment of Family Medicine (KL MacLaughlin), Mayo Clinic, Rochester, Minn.
Xuan ZhuRobert D. and Patricia E. Kern Center for Science of Health Care Delivery (X Zhu), Mayo Clinic, Rochester, Minn.
Lila J Finney RuttenDivision of Epidemiology (RM Jacobson, JL St. Sauver, LJ Finney Rutten), Mayo Clinic, Rochester, Minn.

Funding

"Less Pain, Less Fuss, Right Now!" and "Make It Count!"- Multilevel Interventions for Patient, Parent, and Practice to Enhance Provider Recommendations for HPV VaccinationR01CA217889 · NCI · MAYO CLINIC ROCHESTER · PI GRIFFIN, JOAN M., JACOBSON, ROBERT M. · 2018 to 2023
$2.9M
NCI NIH HHS R01 CA217889
6 · The paper itself

Abstract

objectiveWe sought to determine if our recent trial of human papillomavirus (HPV) vaccine uptake improved influenza, meningococcal ACWY, and tetanus-diphtheria-acellular pertussis (Tdap) vaccine uptake.

methodsWe conducted a secondary analysis of our 4-year factorial stepped-wedge cluster-randomized trial of 6 primary care practices affiliated with the Mayo Clinic. We restricted our analysis to those adolescents 11- to 12-years-old due for at least 1 of 3 vaccines in addition to HPV. Trial arms included 1) usual care, 2) mailed reminder-recall letters to parents of empaneled adolescents following their birthdays alerting parents to the need for HPV vaccination and other vaccines due, 3) monthly confidential audit-feedback reports to providers sent via intracampus mail comparing rates of HPV vaccination for that provider with others, and 4) both interventions. Outcomes included receipt of influenza, meningococcal ACWY, and Tdap vaccines during the study step.

resultsAmong trial participants, 8698 adolescents were due for ≥1 dose HPV and at least 1 of the other vaccines. The parent reminder-recall resulted in a clinically and statistically significant increase in uptake of the other vaccines (odds ratios ranging from 1.44-1.86, all 95% confidence intervals above 1.13) as it did in combination with the provider audit-feedback. Provider audit-feedback alone had no statistically significant impact.

conclusionsThe parent reminder-recall substantially improved uptake of all 3 vaccines, whereas the provider audit-feedback did not. This made sense as the reminder-recall treated all vaccines as equally recommended without a focus on the HPV vaccine due, while the audit-feedback only reported the provider's success with HPV vaccine uptake.

Indexed as

Diphtheria-Tetanus-acellular Pertussis VaccinesInfluenza VaccinesPapillomavirus VaccinesReminder SystemsVaccinationAdolescentChildFemaleHumansMaleMeningococcal VaccinesPapillomavirus InfectionsParentsPrimary Health CareDiphtheria-Tetanus-acellular Pertussis VaccinesInfluenza VaccinesMeningococcal VaccinesPapillomavirus Vaccineschildmedical auditparentsreminder systemsvaccines

Identifiers

PMID40490190
PMCPMC12315576

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.