Evidence map›Paper›PMID 40489860›Full record

Observational studyMedicine2025

Prediction of poor prognosis in patients with sepsis-induced coagulopathy.

Ruimin Tan, Chen Ge, Zinan Yang, He Guo, Zhe Li, Xumin Han, Quansheng Du

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruimin TanSchool of Clinical Medical, North China University of Science and Technology, Tangshan, Hebei Province, China.ORCID 0009-0008-3705-9459
Chen GeCritical Care Department, Hebei General Hospital, Shijiazhuang, Hebei Province, China.
Zinan YangCritical Care Department, Hebei General Hospital, Shijiazhuang, Hebei Province, China.
He GuoCritical Care Department, Hebei General Hospital, Shijiazhuang, Hebei Province, China.
Zhe LiCritical Care Department, Handan Central Hospital, Handan, Hebei Province, The People's Republic of China.
Xumin HanCritical Care Department, Hebei General Hospital, Shijiazhuang, Hebei Province, China.
Quansheng DuCritical Care Department, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Funding

Government Funded Clinical Medical Excellence Training Program 2024008Government funded clinical medical talent training Project 2020003
6 · The paper itself

Abstract

This study aims to evaluate the prognostic value of procalcitonin (PCT), lactate (Lac), and sequential organ failure assessment (SOFA) score in predicting poor outcomes in sepsis-induced coagulopathy (SIC) and develop a predictive model. Data from 96 SIC patients in Hebei General Hospital (September 2020-2023) were analyzed. Patients were divided into survival and death groups based on 28-day outcomes. General data, complications, infection sites, and laboratory parameters were compared. Logistic regression identified independent risk factors, and receiver operating characteristic curve analysis assessed the predictive value of PCT, Lac, SOFA scores, and the combined model. The 28-day mortality was 36.46%. Non-survivors had higher PCT, Lac, SOFA scores, prothrombin time-international normalized ratio, white blood cell count, and intensive care unit stays (P < .05). PCT, Lac, and SOFA scores were independent predictors. The predictive model equation was logit (P = death group) = 0.157 × SOFA score + 0.027 × PCT + 0.187 × Lac - 4.112. The areas under the curve (AUC) of the combined predictive model was 0.809 (95%, confidence intervals [95% CI]: 0.716-0.882), outperformed individual indicators with improved sensitivity and specificity. A combined model of PCT, Lac, and SOFA scores effectively predicts SIC prognosis, aiding clinical decision-making.

Indexed as

Blood Coagulation DisordersSepsisAgedBiomarkersFemaleHumansLactic AcidMaleMiddle AgedOrgan Dysfunction ScoresPredictive Value of TestsProcalcitoninPrognosisRetrospective StudiesRisk FactorsROC CurveBiomarkersLactic AcidProcalcitoninlactateprocalcitoninsepsis-induced coagulopathySOFA score

Identifiers

PMID40489860
PMCPMC12151021

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.