Evidence map›Paper›PMID 40489858›Full record

SynthesisMedicine2025

Efficacy and safety of posterior short-segment versus long-segment pedicle screws fixation for thoracolumbar burst fractures: A systematic review and meta-analysis.

Dandan Yu, Yuxuan Zhang, Xia Li, Wei Wang, Zengming Li, Jun Xiao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dandan YuGuangzhou Special Service Recuperation Center of PLA Rocket Force, Guangzhou, Guangdong, People's Republic of China.
Yuxuan Zhang
Xia Li
Wei Wang
Zengming Li

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effectiveness and safety of fixation levels with pedicle screw fixation for thoracolumbar burst fractures (TLBF).

methodsA systematic and comprehensive literature search was performed from inception to May 2024 in both English and Chinese databases, involving Medline, Cochrane Library, Embase, China National Knowledge Infrastructure Database, Wanfang Database, Chongqing VIP information, and SinoMed. Clinical trials of short-segment fixation and long-segment fixation (LSF) in the treatment of thoracolumbar burst fractures were included. Quality of included trials were assessed according to the methodological index for non-randomized studies (MINORS). Data analysis was conducted by using Review Manager 5.4 software and Stata. The quality of evidence in this systematic review was evaluated using the GRADE evidence quality evaluation system.

resultsSeventeen eligible trials with a total of 1031 patients were included in this meta-analysis. Meta-analysis revealed that intraoperative bleeding (MD = -36.64, 95% CI = -56.36 to -16.92, Z = 3.64, P = .0003) and operation time (MD = -25.73, 95% CI = -46.56 to -4.90, Z = 2.42, P = .02) in the LSF group were higher than those in the short-segment fixation group. There were no significant differences in terms of the final follow-up sagittal index (MD = 1.64, 95% CI = -0.75 to 4.03, Z = 1.35, P = .18) and the final follow-up Oswestry disability index (MD = -2.94, 95% CI = -9.74 to 3.85, Z = 0.85, P = .40) between the 2 groups. The LSF group had the advantages of better the final follow-up Cobb angle (MD = 2.52, 95% CI = 0.35-4.70, Z = 2.27, P = .02), the final follow-up visual analog scale (MD = 0.09, 95% CI = 0.04-0.14, Z = 3.59, P = .0003) and lower the final follow-up implant failure (MD = 3.43, 95% CI = 1.78-6.62, Z = 3.69, P = .0002). The funnel plots and Egger test showed some evidence of asymmetry, suggesting publication bias or small sample effect was existed.

conclusionFor thoracolumbar burst fractures, LSF can better improve patients' low back pain and better maintain postoperative orthopedic effect.

Indexed as

Fracture Fixation, InternalLumbar VertebraePedicle ScrewsSpinal FracturesThoracic VertebraeHumansOperative TimeTreatment Outcomeanalysislongmetasegment fixationshortthoracolumbar burst fractures

Identifiers

PMID40489858
PMCPMC12150920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.