Evidence map›Paper›PMID 40489717›Full record

ArticleNeurology2025

Advance Care Planning and Decision Regret Among Stroke Surrogate Decision Makers: A Longitudinal Cohort Study.

Darin B Zahuranec, Christopher J Becker, Lourdes Carhuapoma, Carmen Ortiz, Rebecca J Lank, Guanghao Zhang, Kevin He, Erin Case, Lewis B Morgenstern

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Darin B ZahuranecDepartment of Neurology, Michigan Medicine, Ann Arbor.ORCID 0000-0002-9772-2469
Christopher J BeckerDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor.ORCID 0000-0003-3414-9826
Lourdes CarhuapomaDivision of Neurosciences Critical Care, The Johns Hopkins Hospital, Baltimore, MD.ORCID 0000-0002-8861-9750
Carmen OrtizDepartment of Neurology, Michigan Medicine, Ann Arbor.ORCID 0009-0004-0191-0177
Rebecca J LankUniversity of Kentucky College of Medicine, Lexington.ORCID 0009-0009-8996-1900
Guanghao ZhangDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor.ORCID 0000-0002-7615-4415
Kevin HeDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor.ORCID 0000-0002-8354-426X
Erin CaseDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor; and.ORCID 0000-0002-4198-454X
Lewis B MorgensternDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor.ORCID 0000-0002-5787-592X

Funding

Outcomes Among Surrogate decision makers In Stroke (OASIS)R01NS091112 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORGENSTERN, LEWIS B, ZAHURANEC, DARIN B · 2015 to 2019
$2.6M
NINDS NIH HHS R01 NS091112
6 · The paper itself

Abstract

objectivesInvestigate the association between advance care planning and decision regret among stroke surrogate decision makers.

methodsPeople hospitalized with ischemic or hemorrhagic stroke and their surrogate decision makers were enrolled. Surrogates completed the validated decision regret scale (range 0-100, higher worse, analyzed as "any" vs "none") in the year after stroke (postdischarge, 3, 6, and 12 months). The association of advance care planning and regret was assessed with multilevel mixed effects logistic regression models, adjusted for prespecified covariates.

resultsParticipants were 317 surrogates for 255 patients with stroke (enrolled April 2016 to October 2020). Patients had a mean age of 74.6 years and mean NIH Stroke Scale of 14.7, with 53% deceased at 3 months. Surrogate characteristics were mean age: 55.8 years, child of patient: 62%, and decision considered (do-not-resuscitate 36%, comfort care 16%, feeding tube 14%, mechanical ventilation 14%, brain surgery 10%, and other 10%). Overall, 132/317 (42%) surrogates reported formal advance care plans. Decision regret scores overall were low (postdischarge mean: 11.2). Formal written advance care plans were associated with lower odds of any decision regret (odds ratio 0.46, 95% CI 0.24-0.89, DISCUSSION: Formal written advance care plans were associated with lower odds of any decision regret among surrogate decision makers in the year after stroke.

Indexed as

Advance Care PlanningDecision MakingEmotionsIschemic StrokeProxyStrokeAgedAged, 80 and overCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID40489717
PMCPMC12151329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.