ArticlePloS one2025
Investigation of locomotive syndrome improvement by total hip arthroplasty in patients with hip osteoarthritis: A before-after comparative study focusing on 25-question geriatric locomotive function scale.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 25-Question Geriatric Locomotive Function Scale (GLFS-25) is one of the tests used to assess the risk of locomotive syndrome (LS). It is a comprehensive tool for measuring LS improvement after total hip arthroplasty (THA) and provides beneficial information for rehabilitation after THA. The primary objective of this study was to clarify LS improvement in patients with hip osteoarthritis (OA) who have undergone unilateral primary THA using GLFS-25. A secondary objective was to identify the impact of THA on each specific GLFS-25 item for optimizing functional recovery.
methodsThe participants of this study were 273 patients who underwent primary THA for hip OA. LS was evaluated using the GLFS-25, stand-up test, and two-step test before receiving THA and three months after THA.
resultsBefore THA, items rated as "moderately difficult" (score ≥2) in GLFS-25 included pain-related Q3 and Q4, activities of daily living (ADL)-related Q12, Q13, Q15, and Q18, and social function-related Q21 and Q23. At three months after THA, these subjective symptoms showed significant improvement. Further analysis of the relationship between these subjective symptom improvements and LS improvement revealed that all items, except pain-related Q3, were significantly associated with LS improvement.
conclusionsPatients experienced not only severe hip pain and physical discomfort but also significant difficulties with activities of daily living (ADL) and social participation before THA. LS improvement after THA was strongly associated with improvements in the subjective symptoms of ADL and social functioning. Based on these findings, rehabilitation strategies that focus on enhancing mobility, improving ADL and social engagement, and optimizing gait function after THA are crucial for further supporting LS recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.