Evidence map›Paper›PMID 40489041›Full record

ArticleNeurology and therapy2025

Dysphagia Management is Associated with Reduced Mortality in Patients with Moderate to Severe Acute Ischemic Stroke.

Julian Frederic Hotz, Lisa Kaindl, Lisa Schneider, Stefan Krebs, Anel Karisik, Dominika Mikšová, Maximilian Bichler, Lavinia Ritscher, Moritz Staudacher, Heimo Lagler and 6 more

Abstract read
In one paragraph

Article in Neurology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

16 authors.

Julian Frederic HotzDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Lisa KaindlDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Lisa SchneiderDepartment of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Stefan KrebsDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Anel KarisikDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Dominika MikšováAustrian National Public Health Institute (Gesundheit Österreich GmbH)/The Austrian National Institute for Quality in Health Care (Bundesinstitut fur Qualität im Gesundheitswesen, BIQG), Vienna, Austria.
Maximilian BichlerDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Lavinia RitscherDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Moritz StaudacherDepartment of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Heimo LaglerDepartment of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Heinz BurgmannDepartment of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Wilfried LangMedical Faculty, Sigmund Freud University Vienna, Vienna, Austria.
Julia FerrariDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria.
Michael KnoflachDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Marek SykoraDepartment of Neurology, St. John's Hospital, Johannes von Gott Platz 1, 1020, Vienna, Austria. marek.sykora@bbwien.at.ORCID http://orcid.org/0000-0003-3508-2176
Austria Stroke Unit Registry Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDysphagia and pneumonia are common complications in patients with acute ischemic stroke (AIS), contributing to increased morbidity and mortality. This study evaluated the impact of pneumonia and dysphagia management strategies (including dysphagia screening, speech therapy, and nasogastric tube use) on patients with AIS outcomes.

methodsThis nationwide, multicenter study included 181,704 patients with AIS from the Austrian Stroke Unit Registry (2006-2024). The impact of pneumonia and the influence of dysphagia management on favorable functional outcome (modified Rankin Scale ≤ 1) and mortality of patients with AIS were calculated using multivariable Poisson regression models.

resultsPneumonia occurred in 15.7% of severely and in 6.7% of moderately affected patients with AIS and was associated with increased mortality (RR 1.61, 95% CI 1.50-1.72, p < 0.05) and inversely with favorable functional outcome (RR 0.37, 95% CI 0.31-0.44, p < 0.05). Dysphagia management was significantly (p < 0.05) associated with reduced mortality, especially in moderately to severely affected patients with AIS, but had a limited impact on functional outcome. After implementation of dysphagia screening, a significant (p < 0.05) decrease in pneumonia prevalence was noted.

conclusionAmong patients with severe acute ischemic stroke, early dysphagia management strategies are associated with reduced mortality, while stroke-associated pneumonia remains a persistent predictor of poor prognosis. These findings underscore the important role of standardized dysphagia management in improving stroke care and patient outcomes.

Indexed as

Acute ischemic strokeDysphagia managementPneumoniaStroke-associated infections

Identifiers

PMID40489041
PMCPMC12255606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.