ReviewScience China. Life sciences2025
Endocrine cancer organoids in basic and translational medical research.
Review in Science China. Life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Targeting SYK to alleviate MDSC-driven immunosuppression and augment anti-PD1 efficacy.Science China. Life sciences · 2026Article
- Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making.Frontiers in endocrinology · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endocrine cancers are a heterogeneous group of malignancies that originate from cells capable of secreting hormones. Examples include but are not limited to thyroid cancer, adrenocortical carcinoma, prostate cancer, and pancreatic cancer. Our limited understanding of endocrine cancers is partially due to constraints related to model systems, which cannot accurately replicate the pathogenesis of these tumors. Patient-derived organoids (PDOs) are clusters of multiple cell types that grow in a three-dimensional environment. They have become innovative models that faithfully reproduce genotype and phenotype of the tissues from which they originated, facilitating the prediction of patient treatment responses and guiding the development of precision medicine. This article provides a comprehensive review of the establishment of endocrine cancer PDOs and their applications in cancer research, drug screening, and personalized therapy. These excellent preclinical models have the potential to advance our understanding of endocrine cancers in basic research and clinical practice. In addition, we discuss the challenges related to current organoid technologies and provide future perspectives on the applications of organoids in precision medicine to improve the management of endocrine cancers.
Indexed as
Identifiers
40488953What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.