Evidence map›Paper›PMID 40488923›Full record

ArticleJournal of autism and developmental disorders2025

Randomized Controlled Trial of Developmental Reciprocity Treatment in Young Children with Autism.

Grace W Gengoux, Katherine Paszek, Maria Estefania Millan, Jared Gong, Rebecca Goodman, Sasha Guillory, Gina Baldi, Robin Libove, Jennifer M Phillips, Antonio Y Hardan

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grace W GengouxStanford University School of Medicine, Stanford, USA. ggengoux@stanford.edu.ORCID http://orcid.org/0000-0002-6942-9513
Katherine PaszekStanford University School of Medicine, Stanford, USA.ORCID http://orcid.org/0009-0009-2365-9637
Maria Estefania MillanStanford University School of Medicine, Stanford, USA.
Jared GongStanford University School of Medicine, Stanford, USA.
Rebecca GoodmanPalo Alto University, Palo Alto, USA.
Sasha GuilloryPalo Alto University, Palo Alto, USA.
Gina BaldiStanford University School of Medicine, Stanford, USA.
Robin LiboveStanford University School of Medicine, Stanford, USA.
Jennifer M PhillipsStanford University School of Medicine, Stanford, USA.
Antonio Y HardanStanford University School of Medicine, Stanford, USA.ORCID http://orcid.org/0000-0002-9860-8625

Funding

Anonymous Donor Anonymous DonorTeresa and Charles Michael Fund for Autism Research Teresa and Charles Michael Fund for Autism Research
6 · The paper itself

Abstract

Developmental social pragmatic interventions for autism spectrum disorder (ASD) focus on development of strong interpersonal relationships by encouraging social communication during joint play routines. The goal of the current investigation was to conduct a randomized controlled 24-week pilot trial to examine the efficacy of a Developmental Reciprocity Treatment package (DRT-P), a developmentally-based intervention that includes both parent training and direct treatment with the child, compared to a delayed treatment group (DTG). Thirty-seven children aged 2-5 years with ASD and language delay were randomized. 83% of parents in DRT-P met fidelity of implementation criteria by 24 weeks. Controlling for fidelity, participants in DRT-P showed significantly greater improvement on the Social Responsiveness Scale Total Score (F = 5.00; p = 0.034) and the Clinical Global Impressions Improvement scale; however no significant group differences were observed on the Brief Observation of Social Communication Change, Vineland Adaptive Behavior Scales, or the MacArthur-Bates Communicative Development Inventories. Findings suggest DRT is a promising intervention for improving some aspects of social functioning in young children with ASD. Future research exploring how behavioral and developmental interventions can be optimally combined to target core social difficulties along with adaptive and functional communication skills is expected to be beneficial.

Indexed as

Developmental interventionsFidelity of implementationParent trainingSocial communication

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.