Evidence map›Paper›PMID 40488917›Full record

ArticleFish physiology and biochemistry2025

Progestogen is a potential trigger initiating sex inversion in rice field eel (Monopterus albus).

Xiancheng Qu, Jiaoyun Jiang, Min Li, Jianhua Ye, Lisa Pan, Qinhua Zhang, Guofang Zhong, Xinchao Zhu, Yifang Du, Xianhui Li

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Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xiancheng Qu *National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China. xcqu@shou.edu.cn.
Jiaoyun Jiang *Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Ministry of Education, Guangxi Normal University, Guilin, 541004, China. Jiangjy@mailbox.gxnu.edu.cn.
Min Li *Colleges of Animal Science and Technology, Jilin Agricultural University, Changchun, 130118, China.
Jianhua YeJiangsu Zhongyang Goup Co., Ltd, Haian, 226600, China.
Lisa PanNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.
Qinhua ZhangNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.
Guofang ZhongNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.
Xinchao ZhuNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.
Yifang DuNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.
Xianhui LiNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China.

Funding

Grant-in-Aid of Jiangsu Zhongyang Group Co., Ltd 001
6 · The paper itself

Abstract

The rice field eel or swamp eel (Monopterus albus) is a hermaphroditic freshwater teleost fish that transitions from a functional female to a functional male. However, the biological mechanism of sex inversion in this species remains unclear. Here we clone the 5' proximal flanking region of the rice field eel dmrt1 gene and find that the progesterone response element (PRE) and androgen response element (ARE) uniquely exist in this region. More importantly, based on reporter gene analysis, in vitro tissue culture, and progestogen hormone level assays, we reveal that progestogen is the prerequisite for the sex inversion of the rice field eel, and androgen plays an important role in the positive regulation of the sex inversion process. Collectively, our results suggest that progestogen is the trigger that initiates the rice field eel's sex trans-differentiation during final oocyte maturation and clarifies the biological mechanism of sex inversion in the rice field eel.

Indexed as

ProgestinsSex Determination ProcessesSmegmamorphaAnimalsEelsFemaleMaleProgesteroneResponse ElementsTranscription FactorsDMRT1 proteinProgesteroneProgestinsTranscription FactorsCis-acting elementsdmrt1Monopterus albusProgestogenSex inversion

Identifiers

PMID40488917

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.