Evidence map›Paper›PMID 40488744›Full record

ArticleeLife2025

Shengze Yao, Yesu Jeon, Barry Kesner, Jeannie T Lee

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. FASEB bioAdvances · 2026
    Article
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  3. Article
  4. Article
  5. Article
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  7. Article
  8. Loss of XIST lncRNA unlocks stemness and cellular plasticity in ovarian cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Shengze YaoDepartment of Molecular Biology, Massachusetts General Hospital, Boston, United States.ORCID https://orcid.org/0000-0003-4195-8402
Yesu JeonDepartment of Molecular Biology, Massachusetts General Hospital, Boston, United States.
Barry KesnerDepartment of Molecular Biology, Massachusetts General Hospital, Boston, United States.
Jeannie T LeeDepartment of Molecular Biology, Massachusetts General Hospital, Boston, United States.ORCID https://orcid.org/0000-0001-7786-8850

Funding

Regulation of X-Inactivation by Non-Coding RNA LociR01GM058839 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, JEANNIE T · 1999 to 2025
$6.7M
Spreading of Xist RNA and Polycomb complexes along the inactive X-chromosome.R01HD097665 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, JEANNIE T · 2019 to 2023
$3.5M
NICHD NIH HHS R01 HD097665NIGMS NIH HHS R01 GM058839NIGMS NIH HHS R01-GM58839NIGMS NIH HHS R01-HD097665
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationRNA, Long NoncodingAnimalsFemaleMiceMouse Embryonic Stem CellsPromoter Regions, GeneticX Chromosome InactivationRNA, Long NoncodingXIST non-coding RNAautosomal targetsgeneticsgenomicsmouseRepeat BX1 inhibitorXist RNA

Identifiers

PMID40488744
PMCPMC12148325

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.