ArticleTranslational vision science & technology2025
Three-Dimensional Choroidal Contour Mapping in Healthy and Diseased Eyes.
Article in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Applying Lincoff's Rule to Central Serous Chorioretinopathy: The Macula Society International CSCR Research Network (MICRoN) Report-15.Ophthalmology science · 2026Article
- Three-Dimensional Choroidal Contour Mapping in Central Serous Chorioretinopathy and Fellow Eyes.Translational vision science & technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Purpose: Quantitative evaluation of choroidal curvature including choroidal inner boundary (CIB) and choroidal outer boundary (COB) and report a comparison between healthy and diseased eyes. Methods: This retrospective study was conducted on 97 eyes of 97 patients. Eyes were divided into three groups: central serous chorioretinopathy (CSCR), dry age-related macular degeneration (AMD), and healthy eyes. Delineation of CIB and COB was performed using a hybrid method based on our previously validated deep learning and three-dimensional (3D) smoothing methods for choroidal layer segmentation. Quantitative analysis of the surfaces was based on best-fit spherical radius (R). R for overall surface, as well as for each region (central/nasal/temporal/superior/inferior region), was estimated. Statistical analysis was done using SPSS software. Results: There were 35 healthy eyes, 32 eyes with CSCR, and 30 eyes with dry AMD. At CIB and COB; RCSCR > Rhealthy > RAMD (P ≤ 0.001). The central region had the lowest R among all the regions within a group at CIB and COB (P < 0.001) in healthy, CSCR, and AMD eyes. There was moderate positive correlation of R of CIB and COB with subfoveal choroidal thickness in healthy eyes and a negligible/weak correlation in CSCR and AMD eyes. Conclusions: Contour of choroid at CIB and COB was the flattest in CSCR and steepest in AMD. Central region was the steepest among all sectors in both healthy and diseased eyes. Translational Relevance: Quantitative study of surface at CIB and COB in diseases helps in understanding the pathophysiological changes and provides a clinical biomarker in disease monitoring and treatment as well.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.