Evidence map›Paper›PMID 40488517›Full record

ReviewApplied and environmental microbiology2025

From genes to function: regulation, maturation, and evolution of cytochrome

Krystina Hird, Julius O Campeciño, Eric L Hegg

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Lysine or histidine? examining the role of the proximal ligand at the active heme center of cytochrome c nitrite reductase.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Microorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Krystina HirdDepartment of Biochemistry & Molecular Biology, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0002-3771-1282
Julius O CampeciñoDepartment of Biochemistry & Molecular Biology, Michigan State University, East Lansing, Michigan, USA.
Eric L HeggDepartment of Biochemistry & Molecular Biology, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0003-2055-5495

Funding

NSF | National Science Foundation Graduate Research Fellowship Program (GRFP) 2235783U.S. Department of Energy DE-SC0017952
6 · The paper itself

Abstract

The dissimilatory nitrate reduction to ammonium pathway converts nitrate to ammonium, a vital reaction in the global nitrogen cycle. The second step of the pathway is performed by cytochrome

Indexed as

Ammonium CompoundsBacteriaBacterial ProteinsCytochromes a1Cytochromes c1Nitrate ReductasesNitratesEvolution, MolecularOxidation-ReductionAmmonium CompoundsBacterial ProteinsCytochromes a1Cytochromes c1nitrate reductase (cytochrome)Nitrate ReductasesNitratescytochrome c nitrite reductasedissimilatory nitrate reduction to ammoniumgene regulationNrfANrfBCDNrfHquinol oxidase

Identifiers

PMID40488517
PMCPMC12285233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.