Observational studyJournal of hepato-biliary-pancreatic sciences2025
New Endoscopic Strategy for Ampullary Tumor and Superficial Nonampullary Duodenal Epithelial Tumor Extending Into Papillary Area.
Observational study in Journal of hepato-biliary-pancreatic sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Endoscopic Papillectomy for Ampullary Tumors in Older Patients: Balancing Oncologic Benefit and Geriatric Risk.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimEndoscopic papillectomy (EP) is widely performed for avoiding high-risk surgeries. However, recurrence rates are high, and lateral extension is a risk for recurrence. With endoscopic submucosal dissection (ESD), even lesions with lateral extensions are able to be en bloc resected, and may reduce that risk. The aim of this study is to validate the adequacy and safety of the new strategy. PATIENTS AND
methodsThis is an exploratory observational study with prospective case enrollment and retrospective analysis. INCLUSION CRITERIA: patients aged 20-85 years with a diagnosis of ampullary tumor or superficial nonampullary duodenal epithelial tumors extending into papilla, and endoscopically resected between December 2020 and April 2023. EP was performed with a lateral extension of < 20 mm, and ESD was performed with 20 mm or more, and the validity of these strategies was verified.
resultsIn total, 40 patients were enrolled, 29 EP and 11 ESD underwent. The en bloc resection rate was 95% (38/40) and endoscopic control was 97.5% (39/40). Adverse events were observed in 27.5% (11/40), with no significant difference in both groups. No serious adverse event was observed.
conclusionsThis strategy based on lateral extension performed very well, and ESD is a useful treatment.
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