Evidence map›Paper›PMID 40488161›Full record

ReviewHeart views : the official journal of the Gulf Heart Association

Cardiac Involvement in Chronic Kidney Disease: Epidemiology, Pathophysiology, and Complications.

Eleni Tzatzaki, Matthaios Didagelos, Eleni Karlafti, Christina Melexopoulou, Dimitrios Tsavdaris, Antonios Ziakas, Smaragdi Marinaki, Haralambos Karvounis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heart views : the official journal of the Gulf Heart Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eleni TzatzakiDivision of Cardiology, Onassis Cardiac Surgery Center, National and Kapodistrian University of Athens, School of Medicine, Laiko Hospital, Athens, Greece.
Matthaios Didagelos1 Cardiology Department, AHEPA University General Hospital, Thessaloniki, Greece.
Eleni KarlaftiDepartment of Emergency, AHEPA University General Hospital, Thessaloniki, Greece.
Christina MelexopoulouDepartment of Nephrology and Renal Transplantation, National and Kapodistrian University of Athens, School of Medicine, Laiko Hospital, Athens, Greece.
Dimitrios Tsavdaris1 Cardiology Department, AHEPA University General Hospital, Thessaloniki, Greece.
Antonios Ziakas1 Cardiology Department, AHEPA University General Hospital, Thessaloniki, Greece.
Smaragdi MarinakiDepartment of Nephrology and Renal Transplantation, National and Kapodistrian University of Athens, School of Medicine, Laiko Hospital, Athens, Greece.
Haralambos Karvounis1 Cardiology Department, AHEPA University General Hospital, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a complex interaction between the heart and kidneys. Cardiac and renal function are both affected physically, chemically, and biologically. In end-stage renal disease (ESRD) patients, cardiovascular disease is the leading cause of mortality. The pathophysiological mechanisms leading to cardiac manifestations in end-stage chronic kidney disease are the decreased oxygen supply to the myocardium, the increased preload, and the left ventricular (LV) afterload alterations. The cardiac complications observed in these patients are LV hypertrophy, myocardial fibrosis, diastolic dysfunction of the left ventricle, coronary artery disease, calcification of the mitral annulus and the aortic valve, and pulmonary hypertension. Several biomarkers that may lead to prevention and early identification of heart complications in these patients are being investigated. In conclusion, the complex relationship between cardiac and renal functions significantly affects patient outcomes in ESRD, highlighting the urgent need for early recognition and intervention strategies to limit cardiovascular complications and improve overall patient care.

Indexed as

Cardiacfailureheartkidneyrenal

Identifiers

PMID40488161
PMCPMC12139650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.